Name: Abaloparatide Subcutaneous
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Uses For abaloparatide
Abaloparatide is used to treat osteoporosis in postmenopausal women who are at high risk for bone fracture. It reduces the risk of having bone and spine fracture in postmenopausal women with osteoporosis.
abaloparatide is available only with your doctor's prescription.
Before Using abaloparatide
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For abaloparatide, the following should be considered:
Tell your doctor if you have ever had any unusual or allergic reaction to abaloparatide or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Appropriate studies have not been performed on the relationship of age to the effects of abaloparatide injection in the pediatric population. Safety and efficacy have not been established. However, use is not recommended in children with open epiphyses (bones are still growing) or genetic disorders.
Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of abaloparatide injection in the elderly. However, elderly patients are more sensitive to the effects of abaloparatide than younger adults.
There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.
Interactions with Medicines
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.
Interactions with Food/Tobacco/Alcohol
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.
Other Medical Problems
The presence of other medical problems may affect the use of abaloparatide. Make sure you tell your doctor if you have any other medical problems, especially:
- Bone cancer, or history of or
- High levels of alkaline phosphatase (enzyme found in the bones) or
- Paget's disease of the bone—Use with caution. May increase the risk of developing bone cancer (osteosarcoma).
- Hypercalcemia (high calcium levels in the blood) or
- Hypercalciuria (high calcium levels in the urine) or
- Hyperparathyroidism (overactive parathyroid) or
- Kidney stones, history of—Use with caution. May cause side effects to become worse.
Precautions While Using abaloparatide
It is very important that your doctor check your progress at regular visits to make sure abaloparatide is working properly. Blood and urine tests may be needed to check for unwanted effects.
abaloparatide may increase your risk of having osteosarcoma (bone cancer). This is more likely to occur if you have a history of radiation treatment involving your bones. Check with your doctor right away if you have bone pain that does not go away or a new soft tissue mass that is tender to palpation.
abaloparatide may cause some people to become dizzy or drowsy. Make sure you know how you react to abaloparatide before you drive, use machines, or do anything else that could be dangerous if you are not alert.
Dizziness, lightheadedness, or fainting may occur, especially when you get up from a lying or sitting position. Getting up slowly may help. If this problem continues or gets worse, check with your doctor.
abaloparatide may increase levels of calcium in the blood and urine. High calcium in the urine may cause kidney stones. Call your doctor right away if you have blood in the urine, confusion, constipation, dry mouth, metallic taste, muscle weakness, nausea or vomiting, pain in the side, back, or abdomen, or weight loss.
Abaloparatide is used to treat bone loss (osteoporosis) for women after menopause who are at high risk of having broken bones (fractures). It is similar to a natural hormone in your body (parathyroid hormone). It works by increasing bone density and strength. This effect helps to decrease the risk of having a fracture.
This medication should not be used for children or young adults whose bones are still growing.
How to use Abaloparatide Pen Injector
Read the Medication Guide and Instructions For Use provided by your pharmacist before you start using abaloparatide and each time you get a refill. If you have any questions, ask your doctor or pharmacist.
If you are using this medication at home, learn all preparation and usage instructions from your health care professional and the product package. Before using, check this product visually for particles or discoloration. If either is present, do not use the liquid.
Before injecting each dose, clean the injection site with rubbing alcohol. Change the injection site each time to lessen injury under the skin.
Inject this medication under the skin of the abdomen area as directed by your doctor, usually once daily. When you give the first several doses, make sure you are in a place where you can sit or lie down if you have dizziness.
Learn how to store and discard medical supplies safely.
Use this medication regularly to get the most benefit from it. To help you remember, use it at the same time each day.
See also Warning section.
Before using abaloparatide, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Before using this medication, tell your doctor or pharmacist your medical history, especially of: other bone disorders (such as bone cancer), high level of calcium in the blood, kidney stones, kidney disease, high level of parathyroid hormone.
This drug may make you dizzy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Limit alcoholic beverages.
Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).
This medication is not usually used in women of childbearing age. It is unlikely to be used during pregnancy or breast-feeding. Consult your doctor if you have any questions about this medication.