AccessPak for HIV PEP Expanded with Kaletra

Name: AccessPak for HIV PEP Expanded with Kaletra

What is the most important information I should know about AccessPak for HIV PEP Expanded with Kaletra (emtricitabine, lopinavir, ritonavir, and tenofovir)?

You should not take this medicine if you have severe liver or kidney disease, or if you are allergic to emtricitabine (Emtriva, Atripla), lopinavir (Kaletra), ritonavir (Norvir), or tenofovir (Viread). Do not take this medicine with other medicines that also contain emtricitabine or tenofovir (Atripla, Emtriva, Viread).

Some medicines can cause unwanted or dangerous effects when used with emtricitabine, lopinavir, ritonavir, and tenofovir. Your doctor may need to change your treatment plan if you use certain medicines.

Get emergency medical help if you have even mild symptoms such as: muscle pain or weakness, numb or cold feeling in your arms and legs, trouble breathing, stomach pain, nausea with vomiting, fast or uneven heart rate, dizziness, or feeling very weak or tired.

What should I discuss with my healthcare provider before taking AccessPak for HIV PEP Expanded with Kaletra (emtricitabine, lopinavir, ritonavir, and tenofovir)?

You should not take this medicine if you have severe liver or kidney disease, or if you are allergic to emtricitabine (Emtriva, Atripla), lopinavir (Kaletra), ritonavir (Norvir), or tenofovir (Viread). Do not take this medicine with other medicines that also contain emtricitabine or tenofovir (Atripla, Emtriva, Viread).

Some medicines can interact with emtricitabine, lopinavir, ritonavir, and tenofovir and should not be used at the same time. Your doctor may need to change your treatment plan if you use any of the following drugs:

  • alfuzosin;

  • lovastatin or simvastatin;

  • St. John's wort;

  • pimozide;

  • midazolam or triazolam;

  • rifampin;

  • sildenafil, Viagra (or Revatio for pulmonary arterial hypertension); or

  • an ergot medicine such as D.H.E. 45, Ergomar, Cafergot, Ergotrate, Methergine, Migergot, or Migranal.

To make sure emtricitabine, lopinavir, ritonavir, and tenofovir is safe for you, tell your doctor if you have:

  • liver or kidney disease;

  • heart disease or heart rhythm disorder;

  • low levels of potassium in your blood;

  • a bleeding disorder such as hemophilia;

  • osteopenia (low bone mineral density); or

  • pancreas problems, diabetes, or high cholesterol.

Some people taking this medicine develop a serious condition called lactic acidosis. This may be more likely in women, in people who are overweight or have liver disease, and in people who have taken HIV/AIDS medication for a long time. Talk with your doctor about your risk.

It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant. HIV can be passed to your baby if you are not properly treated during pregnancy. Take all of your HIV medicines as directed to control your infection.

Women with HIV or AIDS should not breast-feed a baby. Even if your baby is born without HIV, the virus may be passed to the baby in your breast milk.

Do not give this medicine to a child without medical advice.

How should I take AccessPak for HIV PEP Expanded with Kaletra (emtricitabine, lopinavir, ritonavir, and tenofovir)?

Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.

While using this medicine, you may need frequent blood tests at your doctor's office. Your kidney and liver function or bone density may also need to be tested.

HIV/AIDS is usually treated with a combination of drugs. Use all medications as directed by your doctor. Read the medication guide or patient instructions provided with each medication. Do not change your doses or medication schedule without your doctor's advice. Every person with HIV or AIDS should remain under the care of a doctor.

Store at room temperature away from moisture and heat. Do not freeze.

If you have hepatitis B you may develop liver symptoms after you stop taking this medicine, even months after stopping. Your doctor may want to check your liver function for several months after you stop using emtricitabine, lopinavir, ritonavir, and tenofovir.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What other drugs will affect AccessPak for HIV PEP Expanded with Kaletra (emtricitabine, lopinavir, ritonavir, and tenofovir)?

This medicine can harm your kidneys. This effect is increased when you also use certain other medicines, including: antivirals, chemotherapy, injected antibiotics, medicine for bowel disorders, medicine to prevent organ transplant rejection, and some pain or arthritis medicines (including aspirin, Tylenol, Advil, and Aleve). You may need dose adjustments or special tests when taking any of these other medications.

Many drugs can interact with emtricitabine, lopinavir, ritonavir, and tenofovir. Not all possible interactions are listed here. Tell your doctor about all your current medicines and any you start or stop using, especially:

  • any other HIV or AIDS medications;

  • ADHD medication;

  • antibiotic or antifungal medicine;

  • an antidepressant;

  • anti-malaria medication;

  • antiviral medications to treat herpes, HIV, or cytomegalovirus (CMV);

  • asthma or allergy medication;

  • cholesterol-lowering medicine;

  • erectile dysfunction medication (Viagra, Cialis, Levitra);

  • heart or blood pressure medication, heart rhythm medication;

  • insulin or oral diabetes medication;

  • leukemia medication;

  • medicine to treat a psychiatric disorder;

  • migraine headache medicines;

  • narcotic pain medicine;

  • a sedative;

  • seizure medication; or

  • steroid medication (prednisone and others).

This list is not complete and many other drugs can interact with emtricitabine, lopinavir, ritonavir, and tenofovir. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Give a list of all your medicines to any healthcare provider who treats you.

(web3)