Acetaminophen and dextromethorphan

Name: Acetaminophen and dextromethorphan

How should I take acetaminophen and dextromethorphan?

Use exactly as directed on the label, or as prescribed by your doctor. Do not use for longer than recommended. Cough and cold medicine is usually taken only for a short time until your symptoms clear up.

Do not take more of this medication than is recommended. An overdose of acetaminophen can damage your liver or cause death.

Measure liquid medicine with a special dose-measuring spoon or medicine cup. If you do not have a dose-measuring device, ask your pharmacist for one.

The chewable tablet must be chewed before you swallow it.

Drink extra fluids while you are taking this medication.

Call doctor if your symptoms do not improve after 7 days of treatment, or if you have a fever with a headache, cough, or skin rash.

If you need surgery or medical tests, tell the surgeon or doctor ahead of time if you have taken this medicine within the past few days.

Store at room temperature away from moisture, heat, and light. Do not allow liquid medicine to freeze.

What happens if I miss a dose?

Since this medicine is used when needed, you may not be on a dosing schedule. If you are on a schedule, use the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.

Acetaminophen and dextromethorphan side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

In rare cases, acetaminophen may cause a severe skin reaction that can be fatal. This could occur even if you have taken acetaminophen in the past and had no reaction. Stop taking this medicine and call your doctor right away if you have skin redness or a rash that spreads and causes blistering and peeling. If you have this type of reaction, you should never again take any medicine that contains acetaminophen.

Stop using the medicine and call your doctor at once if you have:

  • severe dizziness, anxiety, restless feeling, or nervousness;

  • confusion, hallucinations;

  • slow, shallow breathing;

  • easy bruising or bleeding, unusual weakness, fever, chills, body aches, flu symptoms; or

  • nausea, upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).

Common side effects may include:

  • upset stomach, diarrhea; or

  • feeling irritable.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Usual Adult Dose for Pain

Acetaminophen-dextromethorphan 1000 mg-30 mg/30 mL oral liquid:
30 mL orally every 6 hours not to exceed 120 mL daily.

Acetaminophen-dextromethorphan 325 mg- 5 mg oral capsule:
1 to 2 capsules orally every 6 hours not to exceed 8 capsules daily.

Usual Pediatric Dose for Cold Symptoms

Acetaminophen-dextromethorphan 1000 mg-30 mg/30 mL oral liquid:
12 years or older: 30 mL orally every 6 hours not to exceed 120 mL daily.

Acetaminophen-dextromethorphan 160 mg-5 mg oral tablet, chewable:
2 to 5 years: 1 tablet orally, chewed or dissolved before swallowing, every 4 hours not to exceed 5 tablets daily.
6 to 12 years: 2 tablets orally, chewed or dissolved before swallowing, every 4 hours not to exceed 10 tablets daily.

Acetaminophen-dextromethorphan 160 mg-5 mg/5 mL oral liquid:
4 to 5 years: 5 mL orally every 4 hours not to exceed 25 mL daily.
6 to 12 years: 10 mL orally every 4 hours not to exceed 50 mL daily.

Acetaminophen-dextromethorphan 160 mg-5 mg/5 mL oral suspension:
2 to 5 years: 5 mL orally every 4 hours not to exceed 25 ml daily.
6 to 12 years: 10 mL orally every 4 hours not to exceed 50 mL daily.

Acetaminophen-dextromethorphan 160 mg-7.5 mg/5 mL oral liquid:
2 to 5 years: 5 mL orally every 6 hours not to exceed 20 mL daily.
6 to 12 years: 10 mL orally every 6 hours not to exceed 40 mL daily.

Acetaminophen-dextromethorphan 325 mg- 5 mg oral capsule:
6 to 11 years: 1 capsule every 6 hours not to exceed 4 capsules daily.
12 years or older: 1 to 2 capsules orally every 6 hours not to exceed 8 capsules daily.

Renal Dose Adjustments

Data not available

Precautions

Patients who consume three or more alcohol containing drinks per day should be informed to consult with their physician for advice on when and how to take acetaminophen. Chronic, heavy alcohol users may be at increased risk of liver damage when taking more than recommended dosages.

Patients and adults taking care of children should be advised to consult with their doctor before continuing to use acetaminophen if symptoms of illness worsen. Although rare, there is the possibility of acetaminophen intoxication on chronic use of the drug, and the symptoms seen during the first phase of intoxication (nausea, vomiting, anorexia, malaise, and diaphoresis) may trigger the use of more doses.

Other Comments

Do not crush or chew extended release products.

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