Acetaminophen, Guaifenesin, and Phenylephrine
Name: Acetaminophen, Guaifenesin, and Phenylephrine
- Acetaminophen, Guaifenesin, and Phenylephrine 650 mg
- Acetaminophen, Guaifenesin, and Phenylephrine drug
Dosage Forms
Excipient information presented when available (limited, particularly for generics); consult specific product labeling. [DSC] = Discontinued product
Liquid, Oral:
Mucinex Fast-Max: Acetaminophen 650 mg, guaifenesin 400 mg, and phenylephrine hydrochloride 10 mg per 20 mL (180 mL) [contains brilliant blue fcf (fd&c blue #1), edetate disodium, fd&c red #40, propylene glycol, sodium benzoate, sorbitol]
Mucinex Fast-Max Cold & Sinus: Acetaminophen 650 mg, guaifenesin 400 mg, and phenylephrine hydrochloride 10 mg per 20 mL (177 mL) [contains brilliant blue fcf (fd&c blue #1), edetate disodium, fd&c red #40, propylene glycol, sodium benzoate]
Mucinex Sinus-Max: Acetaminophen 650 mg, guaifenesin 400 mg, and phenylephrine hydrochloride 10 mg per 20 mL (180 mL) [contains brilliant blue fcf (fd&c blue #1), edetate disodium, fd&c red #40, propylene glycol, sodium benzoate]
Mucinex Sinus-Max Congestion: Acetaminophen 650 mg, guaifenesin 400 mg, and phenylephrine hydrochloride 10 mg per 20 mL (180 mL) [contains brilliant blue fcf (fd&c blue #1), edetate disodium, fd&c yellow #10 (quinoline yellow), propylene glycol, sodium benzoate]
Theraflu Warming Cold & Chest: Acetaminophen 325 mg, guaifenesin 200 mg, and phenylephrine hydrochloride 5 mg per 15 mL (245.5 mL [DSC]) [contains benzyl alcohol, edetate disodium, fd&c yellow #6 (sunset yellow), propylene glycol, sodium benzoate; orange flavor]
Tablet, Oral:
CCP Caffeine Free: Acetaminophen 325 mg, guaifenesin 200 mg, and phenylephrine hydrochloride 10 mg [DSC]
GoodSense Cold & Head Congest: Acetaminophen 325 mg, guaifenesin 200 mg, and phenylephrine hydrochloride 5 mg
GoodSense Pressure/Pain/Mucus: Acetaminophen 325 mg, guaifenesin 200 mg, and phenylephrine hydrochloride 5 mg
GoodSense Sinus Relief Max St: Acetaminophen 325 mg, guaifenesin 200 mg, and phenylephrine hydrochloride 5 mg [gluten free; contains fd&c yellow #6 aluminum lake]
GoodSense Sinus Severe Daytime: Acetaminophen 325 mg, guaifenesin 200 mg, and phenylephrine hydrochloride 5 mg
Mucinex Sinus-Max Congestion: Acetaminophen 325 mg, guaifenesin 200 mg, and phenylephrine hydrochloride 5 mg [contains fd&c red #40 aluminum lake, fd&c yellow #6 aluminum lake]
Sudafed PE Pressure+Pain+Mucus: Acetaminophen 325 mg, guaifenesin 200 mg, and phenylephrine hydrochloride 5 mg
Tylenol Cold & Head: Acetaminophen 325 mg, guaifenesin 200 mg, and phenylephrine hydrochloride 5 mg
Tylenol Sinus Congestion/Pain: Acetaminophen 325 mg, guaifenesin 200 mg, and phenylephrine hydrochloride 5 mg [DSC]
Tylenol Sinus Severe: Acetaminophen 325 mg, guaifenesin 200 mg, and phenylephrine hydrochloride 5 mg
Pharmacologic Category
- Alpha-Adrenergic Agonist
- Analgesic, Nonopioid
- Decongestant
- Expectorant
Use Labeled Indications
Allergies/common cold/hay fever: Temporary relief of symptoms (eg, headache, minor aches/pains, nasal congestion, sinus congestion/pressure) associated with hay fever, other respiratory allergies, or the common cold; temporarily reduces fever; helps loosen phlegm and thin bronchial secretions.
Contraindications
OTC labeling: When used for self-medication, do not use with any other drug containing acetaminophen; in combination with or within 14 days of stopping a monoamine oxidase inhibitor (MAOI); if you are hypersensitive to acetaminophen, guaifenesin, phenylephrine, or any component of the formulation.
Dosing Pediatric
Allergies/common cold/hay fever: Oral: Children ≥12 years and Adolescents: Refer to adult dosing
Adverse Reactions
See individual agents.