Acyclovir (Systemic)
Name: Acyclovir (Systemic)
Brand Names U.S.
- Zovirax
Special Populations Elderly
Increased plasma concentrations.
Dosing Geriatric
Refer to adult dosing.
Dosing Obesity
Obese patients should be dosed using ideal body weight.
Administration
Oral: May be administered with or without food.
IV: Avoid rapid infusion; infuse over 1 hour to prevent renal damage; maintain adequate hydration of patient; check for phlebitis and rotate infusion sites. Avoid IM or SubQ administration.
Dietary Considerations
May be taken with or without food. Some products may contain sodium.
Storage
Capsule, oral suspension, tablet: Store at controlled room temperature of 15°C to 25°C (59°F to 77°F); protect from capsule and tablet from moisture.
Injection: Store powder at controlled room temperature of 15°C to 25°C (59°F to 77°F). Reconstituted solutions remain stable for 12 hours at room temperature. Do not refrigerate reconstituted solutions or solutions diluted for infusion as they may precipitate. Once diluted for infusion with NS or D5W, use within 24 hours.
Monitoring Parameters
Urinalysis, BUN, serum creatinine, liver enzymes, CBC