Name: Adipost

How should I take Adipost (phendimetrazine)?

Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label. Phendimetrazine should be taken only for a short time, such as a few weeks.

Phendimetrazine is usually taken once daily. Follow your doctor's instructions.

Take phendimetrazine on an empty stomach, 30 to 60 minutes before your morning meal.

Do not crush, chew, break, or open the extended-release capsule. Swallow it whole. Breaking or opening the pill may cause too much of the drug to be released at one time.

You should lose at least 4 pounds during the first 4 weeks of taking phendimetrazine and eating a low calorie diet. Tell your doctor if you do not lose at least 4 pounds after taking the medication for 4 weeks.

Do not stop using phendimetrazine suddenly after long-term use, or you could have unpleasant withdrawal symptoms. Ask your doctor how to avoid withdrawal symptoms when you stop using phendimetrazine.

Never take more of this medication than is prescribed for you. Too much phendimetrazine could be very dangerous to your health. Talk with your doctor if you have increased hunger or if you otherwise think the medication is not working properly. Taking more of this medication will not make it more effective and can cause serious, life-threatening side effects.

Store at room temperature away from moisture and heat. Keep the bottle tightly closed when not in use.

What should I avoid while taking Adipost (phendimetrazine)?

Phendimetrazine may cause blurred vision or impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert and able to see clearly.

Drinking alcohol can increase certain side effects of phendimetrazine.

Adipost (phendimetrazine) side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using phendimetrazine and call your doctor at once if you have a serious side effect such as:

  • feeling short of breath, even with mild exertion;

  • chest pain, feeling like you might pass out;

  • swelling in your ankles or feet;

  • pounding heartbeats or fluttering in your chest;

  • confusion or irritability, unusual thoughts or behavior;

  • feelings of extreme happiness or sadness; or

  • dangerously high blood pressure (severe headache, blurred vision, buzzing in your ears, anxiety, confusion, chest pain, shortness of breath, uneven heartbeats, seizure).

Less serious side effects may include:

  • feeling restless or hyperactive;

  • headache, dizziness, tremors;

  • sleep problems (insomnia);

  • flushing (warmth, redness, or tingly feeling);

  • dry mouth;

  • diarrhea or constipation, upset stomach; or

  • increased or decreased interest in sex, impotence.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Liver Dose Adjustments

Data not available

Phendimetrazine Pregnancy Warnings

-Extended-release: This drug is contraindicated during pregnancy. -Immediate-release: Safety has not been established during pregnancy; this drug should not be used during pregnancy unless the benefit outweighs the risk to the fetus. US FDA pregnancy category: X (extended-release) US FDA pregnancy category: C (immediate-release) Comments: Animal reproduction and fertility studies have not been conducted with this drug.

US FDA pregnancy category X: Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use of the drug in pregnant women clearly outweigh potential benefits. US FDA pregnancy category C: Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

Phendimetrazine Breastfeeding Warnings

A decision should be made to discontinue breastfeeding or discontinue the drug, taking into account the importance of the drug to the mother. Excreted into human milk: Unknown Excreted into animal milk: Data not available Comments: This drug has pharmacological activity similar to the amphetamines; amphetamines are present in human milk.