Akbeta

Name: Akbeta

What special precautions should I follow?

Before using levobunolol eye drops,

  • tell your doctor and pharmacist if you are allergic to levobunolol, other beta blockers, sulfites, or any other drugs.
  • tell your doctor and pharmacist what prescription and nonprescription medications you are taking, especially other eye medications, beta blockers, such as atenolol (Tenormin), carteolol (Cartrol), labetalol (Normodyne, Trandate), metoprolol (Lopressor), nadolol (Corgard), propranolol (Inderal), sotalol (Betapace), or timolol (Blocadren); quinidine (Quinidex, Quinaglute Dura-Tabs); verapamil (Calan, Isoptin); and vitamins.
  • tell your doctor if you have or have ever had thyroid, heart, or lung disease; congestive heart failure; or diabetes.
  • tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while using levobunolol eye drops, call your doctor.
  • if you are having surgery, including dental surgery, tell the doctor or dentist that you are using levobunolol eye drops.
  • if you are using another topical eye medication, instill it at least 10 minutes before or after you instill levobunolol eye drops.

What should I do if I forget a dose?

Instill the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not instill a double dose to make up for a missed one.

How should I use Akbeta (levobunolol ophthalmic)?

Use levobunolol ophthalmic exactly as it was prescribed for you. Do not use the medication in larger amounts, or use it for longer than recommended by your doctor. Follow the instructions on your prescription label.

Wash your hands before using the eye drops.

Do not use this medication while you are wearing contact lenses. Levobunolol ophthalmic may contain a preservative that can be absorbed by soft contact lenses. Wait at least 15 minutes after using levobunolol before putting your contact lenses in.

To apply the eye drops:

  • Tilt your head back slightly and pull down your lower eyelid. Hold the dropper above the eye with the dropper tip down. Look up and away from the dropper as you squeeze out a drop, then close your eye.

  • Gently press your finger to the inside corner of the eye (near your nose) for about 1 minute to keep the liquid from draining into your tear duct. If you use more than one drop in the same eye, wait about 5 minutes before putting in the next drop.

  • Do not allow the dropper tip to touch any surface, including the eyes or hands. If the dropper becomes contaminated it could cause an infection in your eye, which can lead to vision loss or serious damage to the eye.

Do not use the eye drops if the liquid has changed colors or has particles in it. Call your doctor for a new prescription.

Tell your doctor right away if you have any eye injury or infection. If you have any type of surgery, tell the surgeon ahead of time that you are using levobunolol ophthalmic. You may need to stop using the medicine for a short time.

Store this medication at room temperature away from moisture, heat, and light. Keep the bottle tightly closed when not in use.

What other drugs will affect Akbeta (levobunolol ophthalmic)?

Before using levobunolol ophthalmic, tell your doctor if you are using any of the following drugs:

  • digoxin (digitalis, Lanoxin);

  • reserpine;

  • insulin or diabetes medications you take by mouth;

  • any other beta-blocker such as atenolol (Tenormin), bisoprolol (Zebeta), labetalol (Normodyne, Trandate), metoprolol (Lopressor, Toprol), nadolol (Corgard), propranolol (Inderal, InnoPran), timolol (Blocadren), and others;

  • a calcium channel blocker such as amlodipine (Norvasc), diltiazem (Tiazac, Cartia, Cardizem), felodipine (Plendil), nifedipine (Nifedical, Procardia, Adalat), verapamil (Calan, Covera, Isoptin, Verelan); or

  • medicines to treat psychiatric disorders, such as chlorpromazine (Thorazine), haloperidol (Haldol), mesoridazine (Serentil), or thioridazine (Mellaril).

This list is not complete and there may be other drugs that can interact with levobunolol ophthalmic. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Usual Adult Dose for Intraocular Hypertension

0.25% solution: One to two drops in the affected eye(s) twice a day
0.5% solution: One to two drops in the affected eye(s) once a day

Comments:
-In patients with more severe or uncontrolled glaucoma, the 0.5% solution can be administered twice a day.
-If intraocular pressure is not at a satisfactory level, concomitant therapy with dipivefrin and/or epinephrine, and/or pilocarpine and other miotics, and/or systemically administered carbonic anhydrase inhibitors, such as acetazolamide, can be instituted.
-Patients should not use two or more topical ophthalmic beta-adrenergic blocking drugs concomitantly.

Use: Lowering intraocular pressure in patients with chronic open-angle glaucoma and intraocular hypertension

Usual Adult Dose for Glaucoma (Open Angle)

0.25% solution: One to two drops in the affected eye(s) twice a day
0.5% solution: One to two drops in the affected eye(s) once a day

Comments:
-In patients with more severe or uncontrolled glaucoma, the 0.5% solution can be administered twice a day.
-If intraocular pressure is not at a satisfactory level, concomitant therapy with dipivefrin and/or epinephrine, and/or pilocarpine and other miotics, and/or systemically administered carbonic anhydrase inhibitors, such as acetazolamide, can be instituted.
-Patients should not use two or more topical ophthalmic beta-adrenergic blocking drugs concomitantly.

Use: Lowering intraocular pressure in patients with chronic open-angle glaucoma and intraocular hypertension

Renal Dose Adjustments

Data not available

Levobunolol Identification

Substance Name

Levobunolol

CAS Registry Number

47141-42-4

Drug Class

Antihypertensive Agents

Adrenergic Beta-Antagonists

Antiglaucoma Agents

Antiarrhythmics

Administrative Information

LactMed Record Number

292

Last Revision Date

20130907

Disclaimer

Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.

(web3)