Name: Alcaftadine

Alcaftadine Drug Class

Alcaftadine is part of the drug class:

  • Other antiallergics

Alcaftadine Precautions

Serious side effects have been reported with alcaftadine including the following:

  • Eye infections. Avoid allowing the tip of the alcaftadine bottle to contact the eyeball, fingers, surrounding structures, or any other surfaces in order to avoid contamination by common bacteria known to cause eye infections. Serious damage to the eye and subsequent loss of vision may result from using contaminated alcaftadine. Tell your healthcare provider right away if you have any of the following symptoms of an infection:
  • sore throat
  • fever or chills
  • unusual discharge from the eye
  • eye pain

Alcaftadine should not be used to treat contact lens-related irritation and should not be administered while wearing contact lenses. The preservative in alcaftadine, benzalkonium chloride, may be absorbed by soft contact lenses.

Remove contact lenses prior to administration of alcaftadine. Contact lenses may be reinserted after 10 minutes following administration of alcaftadine.

Do not take alcaftadine if you are allergic to alcaftadine or to any of its ingredients.

Alcaftadine can also cause blurred vision. Do not drive or operate heavy machinery until you know how alcaftadine affects you.

Dosing Adult

Allergic conjunctivitis: Ophthalmic: Instill 1 drop into each eye once daily.

Dosing Pediatric

Allergic conjunctivitis: Ophthalmic: Children ≥2 years and Adolescents: Refer to adult dosing.

Dosing Renal Impairment

There are no dosage adjustments provided in the manufacturer’s labeling.


Store at 15°C to 25°C (59°F to 77°F).

Drug Interactions

There are no known significant interactions.

For the Consumer

Applies to alcaftadine ophthalmic: ophthalmic solution

Along with its needed effects, alcaftadine ophthalmic may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking alcaftadine ophthalmic:

Less common
  • Burning or stinging sensation in the eye
  • itching of the eyes
  • red, sore eyes

Some side effects of alcaftadine ophthalmic may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common
  • Chills
  • cough
  • diarrhea
  • fever
  • general feeling of discomfort or illness
  • headache
  • joint pain
  • loss of appetite
  • muscle aches and pains
  • nausea
  • runny nose
  • shivering
  • sore throat
  • stuffy or runny nose
  • sweating
  • trouble sleeping
  • unusual tiredness or weakness
  • vomiting

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Alcaftadine ophthalmic Pregnancy Warnings

Animal studies have failed to reveal evidence of teratogenicity. There are no controlled data in human pregnancy. US FDA pregnancy category B: Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.

This drug should be used during pregnancy only if clearly needed. US FDA pregnancy category: B