Alferon N

Name: Alferon N

Interferon Alfa N3 Dosage

Interferon alfa-n3 is injected directly into each genital wart lesion. You will receive this injection in a clinic setting.

Interferon alfa-n3 injections are usually given 2 times per week for up to 8 weeks.

Your lesions may only partially clear up by the end of your 8-week treatment. However, you may continue to notice improvement even after your treatment ends.

Tell your doctor if your warts do not completely clear up within 3 months after your last injection of interferon alfa-n3.

To reduce or prevent certain side effects, your doctor may recommend you take acetaminophen (Tylenol) at the time of your interferon alfa-n3 injections. Follow your doctor's instructions about the correct dose.

Seek emergency medical attention if you think you have received too much of this medicine.

Symptoms of an interferon alfa-n3 overdose are not known.

Call your doctor for instructions if you miss an appointment for your interferon alfa-n3 injection.

Warning

This medication can infrequently cause or worsen serious (rarely fatal) medical conditions, including mental/mood conditions (e.g., depression), immune system problems (autoimmune conditions such as lupus or rheumatoid arthritis), circulation problems, or infections. If your medical history includes any of these conditions, tell your doctor promptly. Also, tell your doctor immediately if any serious symptoms or side effects occur (see Side Effects section).

This medication may be combined with ribavirin to treat chronic hepatitis C. Ribavirin may cause harm to an unborn baby or death. Women must avoid pregnancy while they or their male partners are using ribavirin. Ribavirin may cause a blood disorder (hemolytic anemia), which can worsen heart disease. If you are using this medication with ribavirin to treat chronic hepatitis C, also carefully read the drug information for ribavirin.

How to use

Read the Medication Guide available from your pharmacist before you start using this drug and each time you get a refill. Learn all preparation and usage instructions given by the manufacturer. If you have any questions, consult your doctor or pharmacist.This medication is given by injection into a muscle or under the skin as directed by your doctor. Rotate the injection site each time you inject this medication to prevent soreness. It may also be given by injection into a vein or directly into a lesion, usually by a health care professional.If you are giving this medication to yourself at home, learn all preparation and usage instructions from your health care professional. Do not shake the medication container (vial or syringe). Doing so may decrease the effectiveness of the drug. Before using, check this product visually for particles or discoloration. If either is present, do not use the liquid. Learn how to store and discard medical supplies safely. Never reuse single-use syringes or needles. It is okay to reuse the multidose pen. It is best used in the evening before bedtime to reduce side effects.Drink plenty of fluids while using this medication unless otherwise directed by your doctor.Dosage is based on your medical condition and response to therapy. Do not change the dose or how often you use this medication without your doctor's approval. Use this medication regularly to get the most benefit from it. To help you remember, use it at the same time each evening that you have a scheduled dose.Different brands of interferon alfa can result in different amounts of medication in the blood. This medication comes in different forms (a powder in a vial, a solution in a vial, and a multidose pen). The way you inject this medication depends on the form you are using. Follow your doctor's directions carefully. Do not switch brands without your doctor's permission.

Notes

Do not share this medication with others.Laboratory and/or medical tests (such as blood counts, thyroid tests, kidney/liver function, triglyceride levels, eye exams) should be performed before you start treatment, periodically to monitor your progress, or to check for side effects. Depending on your medical history, other tests (such as EKG) may be needed. Consult your doctor for more details.Do not change brands of interferon without checking with your doctor or pharmacist. Other interferons may not have the same effects on your disease.

How is Alferon N (interferon alfa-n3)given?

Interferon alfa-n3 is injected directly into each genital wart lesion. You will receive this injection in a clinic setting.

Interferon alfa-n3 injections are usually given 2 times per week for up to 8 weeks.

Your lesions may only partially clear up by the end of your 8-week treatment. However, you may continue to notice improvement even after your treatment ends.

Tell your doctor if your warts do not completely clear up within 3 months after your last injection of interferon alfa-n3.

To reduce or prevent certain side effects, your doctor may recommend you take acetaminophen (Tylenol) at the time of your interferon alfa-n3 injections. Follow your doctor's instructions about the correct dose.

What happens if I miss a dose?

Call your doctor for instructions if you miss an appointment for your interferon alfa-n3 injection.

What are some things I need to know or do while I take Alferon N?

  • Tell all of your health care providers that you take Alferon N. This includes your doctors, nurses, pharmacists, and dentists.
  • Have blood work checked as you have been told by the doctor. Talk with the doctor.
  • This medicine is made from human plasma (part of the blood) and may have viruses that may cause disease. This medicine is screened, tested, and treated to lower the chance that it carries an infection. Talk with the doctor.
  • Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using this medicine while you are pregnant.
  • Tell your doctor if you are breast-feeding. You will need to talk about any risks to your baby.

Adverse Effects

>10%

Myalgia (45%)

Fever (40%)

Headache (31%)

Chills (14%)

Fatigue (14%)

Decreased WBC

1-10%

Dizziness (9%)

Depression

Insomnia

Pruritus

Diarrhea

Dyspepsia

Taste disturbance

Nausea/vomiting

Nose bleed

Groin and lymph node swelling

Pharyngitis

Arthralgia

Visual disturbance

Back pain

Paresthesia

Thirst

Patient Handout

Print without Office InfoPrint with Office Info

Usual Adult Dose for Condylomata Acuminata

Refractory or recurring external condylomata acuminata: 0.05 mL (250,000 international units) per wart, injected intralesionally twice a week for up to 8 weeks

The maximum recommended dosage per treatment session is 0.5 mL (2.5 million international units).

(web3)