Alkeran I.V. oral / injection

Name: Alkeran I.V. oral / injection

What should I discuss with my healthcare provider before using Alkeran I.V. (melphalan oral/injection)?

You should not use melphalan if you are allergic to it, or if prior treatment with this medication was unsuccessful in controlling your disease.

To make sure melphalan is safe for you, tell your doctor if you have:

  • a weak immune system (caused by disease or by using certain medicine);

  • liver disease;

  • kidney disease; or

  • a history of chemotherapy or radiation.

Using melphalan may increase your risk of developing other types of cancer, such as leukemia. Ask your doctor about your specific risk.

Do not use melphalan if you are pregnant. It could harm the unborn baby. Use effective birth control to avoid pregnancy during your treatment with melphalan. Follow your doctor's instructions about how long to prevent pregnancy after your treatment ends.

This medication may affect fertility (your ability to have children), whether you are a man or a woman.

It is not known whether melphalan passes into breast milk or if it could harm a nursing baby. You should not breast-feed while using this medicine.

How is Alkeran I.V. (melphalan oral/injection) given?

Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results. Do not take this medicine in larger or smaller amounts or for longer than recommended.

Oral melphalan is a tablet you take by mouth. Injectable melphalan is injected into a vein through an IV. A healthcare provider will give you this injection.

Your doctor will perform blood tests to make sure you do not have conditions that would prevent you from safely using melphalan.

Melphalan can lower blood cells that help your body fight infections and help your blood to clot. This can make it easier for you to bleed from an injury or get sick from being around others who are ill. Your blood may need to be tested often.

Store melphalan tablets in the refrigerator and protect them from light.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What other drugs will affect Alkeran I.V. (melphalan oral/injection)?

Other drugs may interact with melphalan, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.

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