- Alomide uses
- Alomide other uses for
- Alomide missed dose
- Alomide drug
- Alomide 3 mg
- Alomide oral dose
- Alomide action
- Alomide side effects
- Alomide effects of
Other uses for this medicine
This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.
What should I do if I forget a dose?
Instill the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not instill a double dose to make up for a missed one.
How to store lodoxamide eye drops
- Keep all medicines out of the reach and sight of children.
- Store in a cool, dry place, away from direct heat and light.
- Eye drops only keep for four weeks once the bottle has been opened, so do not use lodoxamide drops if the bottle has been open for longer than this. This will help to prevent the risk of eye infections.
What happens if I overdose?
Seek emergency medical attention if you think you have used too much of this medicine.
An overdose of lodoxamide ophthalmic applied to the eyes is not likely to occur.
What other drugs will affect Alomide (lodoxamide ophthalmic)?
It is not likely that other drugs you take orally or inject will have an effect on lodoxamide ophthalmic. But many drugs can interact with each other. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.
Lodoxamide tromethamine is a mast cell stabilizer that inhibits the in vivo Type I immediate hypersensitivity reaction. Lodoxamide therapy inhibits the increases in cutaneous vascular permeability that are associated with reagin or IgE and antigen-mediated reactions.
In vitro studies have demonstrated the ability of lodoxamide to stabilize rodent mast cells and prevent antigen-stimulated release of histamine. In addition, lodoxamide prevents the release of other mast cell inflammatory mediators (i.e., SRS-A, slow-reacting substances of anaphylaxis, also known as the peptidoleukotrienes) and inhibits eosinophil chemotaxis. Although lodoxamide's precise mechanism of action is unknown, the drug has been reported to prevent calcium influx into mast cells upon antigen stimulation.
Lodoxamide has no intrinsic vasoconstrictor, antihistaminic, cyclooxygenase inhibition, or other anti-inflammatory activity.
The disposition of 14C-lodoxamide was studied in six healthy adult volunteers receiving a 3 mg (50 μCi) oral dose of lodoxamide. Urinary excretion was the major route of elimination. The elimination half-life of 14C-lodoxamide was 8.5 hours in urine. In a study conducted in twelve healthy adult volunteers, topical administration of Alomide® (lodoxamide tromethamine ophthalmic solution) 0.1%, one drop in each eye four times per day for ten days, did not result in any measurable lodoxamide plasma levels at a detection limit of 2.5 ng/mL.
Indications and usage
Alomide® (lodoxamide tromethamine ophthalmic solution) 0.1% is indicated in the treatment of the ocular disorders referred to by the terms vernal keratoconjunctivitis, vernal conjunctivitis, and vernal keratitis.
If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.
During clinical studies of ALOMIDE® (lodoxamide tromethamine ophthalmic solution) 0.1%, the most frequently reported ocular adverse experiences were transient burning, stinging, or discomfort upon instillation, which occurred in approximately 15% of the subjects. Other ocular events occurring in 1 to 5% of the subjects included ocular itching/pruritus, blurred vision, dry eye, tearing/discharge, hyperemia, crystalline deposits, and foreign body sensation. Events that occurred in less than 1% of the subjects included corneal erosion/ulcer, scales on lid/lash, eye pain, ocular edema/swelling, ocular warming sensation, ocular fatigue, chemosis, corneal abrasion, anterior chamber cells, keratopathy/keratitis, blepharitis, allergy, sticky sensation, and epitheliopathy.
Nonocular events reported were headache (1.5%) and (at less than 1%) heat sensation, dizziness, somnolence, nausea, stomach discomfort, sneezing, dry nose, and rash.
Read the entire FDA prescribing information for Alomide (Lodoxamide Tromethamine)Read More »
For the Consumer
Applies to lodoxamide ophthalmic: ophthalmic solutionSide Effects of This Medicine
Along with its needed effects, lodoxamide ophthalmic (the active ingredient contained in Alomide) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor as soon as possible if any of the following side effects occur while taking lodoxamide ophthalmic:Less common
- Blurred vision
- feeling of something in eye, itching, discomfort, redness, tearing or discharge, or other eye or eyelid irritation (not present before you started using this medicine or becoming worse while you are using this medicine)
- mucus from eye, eye pain, or swelling of eye or eyelid (not present before you started using this medicine or becoming worse while you are using this medicine)
- sensitivity of eyes to light
- skin rash
Some side effects of lodoxamide ophthalmic may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:More common
- Burning or stinging (when medicine is applied)
- Aching eyes
- crusting in corner of eye or on eyelid
- drowsiness or sleepiness
- dryness of nose or eyes
- feeling of heat in eye
- heat sensation on body
- nausea or stomach discomfort
- scales on eyelid or eyelash
- sticky feeling of eyes
- tired eyes