Aloquin (Iodoquinol)

Name: Aloquin (Iodoquinol)

How is this medicine (Aloquin) best taken?

Use this medicine as ordered by your doctor. Read all information given to you. Follow all instructions closely.

  • To gain the most benefit, do not miss doses.
  • Keep taking Aloquin as you have been told by your doctor or other health care provider, even if you feel well.
  • Take after meals.

What do I do if I miss a dose?

  • Take a missed dose as soon as you think about it.
  • If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
  • Do not take 2 doses at the same time or extra doses.

What are some side effects that I need to call my doctor about right away?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

  • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
  • Numbness, pain, tingling, or cold feeling of the hands or feet.
  • Change in eyesight.
  • Throwing up.

If OVERDOSE is suspected

If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

Consumer Information Use and Disclaimer

  • If your symptoms or health problems do not get better or if they become worse, call your doctor.
  • Do not share your drugs with others and do not take anyone else's drugs.
  • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
  • Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
  • Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about this medicine, please talk with your doctor, nurse, pharmacist, or other health care provider.
  • If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

This information should not be used to decide whether or not to take Aloquin or any other medicine. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Aloquin. This information is not specific medical advice and does not replace information you receive from the healthcare provider. You must talk with the healthcare provider for complete information about the risks and benefits of using this medicine.

Review Date: October 4, 2017

For the Consumer

Applies to iodoquinol: oral tablet

Along with its needed effects, iodoquinol may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking iodoquinol:

Less common
  • Fever or chills
  • skin rash, hives, or itching
  • swelling of neck
With long-term use of high doses - especially in children
  • Blurred vision or any change in vision
  • clumsiness or unsteadiness
  • decreased vision or eye pain
  • increased weakness
  • muscle pain
  • numbness, tingling, pain, or weakness in hands or feet

Some side effects of iodoquinol may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common
  • Diarrhea
  • nausea or vomiting
  • stomach pain
Less common
  • Headache
  • itching of the rectal area

For Healthcare Professionals

Applies to iodoquinol: compounding powder, oral tablet

Gastrointestinal

Gastrointestinal side effects have included nausea, vomiting, abdominal cramps, diarrhea, and pruritus ani.[Ref]

Nervous system

Some neuropathy may be irreversible. Seizures and encephalopathy have been reported in at least one patient. Optic atrophy has been reported, generally in children being treated for acrodermatitis enteropathica at daily dosages between 1300 to 3600 mg for up to two years. Visual deterioration is generally irreversible.

Clioquinol, another hydroxyquinoline, was associated with several thousand cases of subacute myelo-optic neuropathy in Japan, leading to its removal from the market. This syndrome consisted of peripheral weakness, spastic paraparesis, dysesthesia, and optic neuropathy.

Because of the neurotoxicity associated with iodoquinol and its growing use in pediatric patients for the treatment of nonspecific chronic diarrhea in the 1970's, the American Academy of Pediatrics Committee on Drugs issued a statement recommending that products containing clioquinol or iodoquinol not be used in pediatric patients.[Ref]

Nervous system side effects have been reported rarely. These have included peripheral neuropathy and headache. Optic atrophy has been reported, generally in pediatric patients receiving large doses for long periods of time.[Ref]

Dermatologic

Dermatologic side effects have included acneiform papular or pustular skin eruptions, bulla, urticaria, and pruritus. These reactions are related to the iodine content of iodoquinol.[Ref]

Other

Other side effects have included fever, chills, and enlargement of the thyroid.[Ref]

Some side effects of iodoquinol may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

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