Alti-Amoxi Clav

Name: Alti-Amoxi Clav

Important information

You should not use this medicine if you have severe kidney disease, if you have had liver problems or jaundice while taking amoxicillin and clavulanate potassium, or if you are allergic to any penicillin or cephalosporin antibiotic, such as Amoxil, Ceftin, Cefzil, Levaquin, Moxatag, Omnicef, and others.

If you switch from one tablet form to another (regular, chewable, or extended-release tablet), take only the new tablet form and strength prescribed for you. Amoxicillin and clavulanate may not be as effective or could be harmful if you do not use the exact tablet form your doctor has prescribed.

Amoxicillin and clavulanate potassium can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

Amoxicillin and clavulanate potassium can make birth control pills less effective. Ask your doctor about using a non-hormone method of birth control (such as a condom, diaphragm, spermicide) to prevent pregnancy while taking amoxicillin and clavulanate potassium.

Usual Adult Dose for Febrile Neutropenia

Low-risk: 500 mg orally every 8 hours in combination with ciprofloxacin until the patient has been afebrile for at least 24 hours and the absolute neutrophil count is more than 500 cells/mm3

Usual Pediatric Dose for Sinusitis

Less than 12 weeks:
125 mg/5 mL oral suspension: 15 mg/kg orally every 12 hours

3 months (12 weeks) or older:
Less than 40 kg:
125 mg/5 mL or 250 mg/5 mL oral suspension: 6.67 to 13.33 mg/kg orally every 8 hours
200 mg/5 mL or 400 mg/5 mL oral suspension or chewable tablets: 12.5 to 22.5 mg/kg orally every 12 hours
600 mg/5 mL oral suspension: 45 mg/kg orally every 12 hours

40 kg or more:
Immediate release tablets: 250 mg orally every 8 hours or 500 mg orally every 12 hours; for more severe infections, 500 mg orally every 8 hours or 875 mg orally every 12 hours may be administered

Extended release tablets: 2 g (2 tablets) orally every 12 hours for 10 days

Upsides

  • Effective against more organisms than amoxicillin by itself.
  • Available in tablet, chewable tablet, extended-release and liquid formulations.

Bottom Line

Amoxicillin/clavulanate is a combination penicillin-type antibiotic that effectively treats a variety of infections. Use may be limited by resistance and side effects such as diarrhea and yeast overgrowth.

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