Amcinonide Topical application

Name: Amcinonide Topical application

For the Consumer

Applies to amcinonide topical: topical application cream, topical application lotion, topical application ointment

Along with its needed effects, amcinonide topical may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking amcinonide topical:

Incidence not known
  • Blistering, burning, crusting, dryness, or flaking of the skin
  • irritation
  • itching, scaling, severe redness, soreness, or swelling of the skin
  • redness and scaling around the mouth
  • thinning of the skin with easy bruising, especially when used on the face or where the skin folds together (e.g. between the fingers)

Some side effects of amcinonide topical may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Incidence not known
  • Acne or pimples
  • burning and itching of the skin with pinhead-sized red blisters
  • burning, itching, and pain in hairy areas, or pus at the root of the hair
  • increased hair growth on the forehead, back, arms, and legs
  • lightening of normal skin color
  • lightening of treated areas of dark skin
  • reddish purple lines on the arms, face, legs, trunk, or groin
  • softening of the skin

For Healthcare Professionals

Applies to amcinonide topical: topical cream, topical lotion, topical ointment

General

The most commonly reported side effects were itching, stinging, soreness, and burning.[Ref]

Endocrine

Frequency not reported: Hypothalamic-pituitary-adrenal (HPA) axis suppression, Cushing's syndrome[Ref]

Nervous system

Frequency not reported: Intracranial hypertension (including bulging fontanelles, headaches, bilateral papilledema)[Ref]

Metabolic

Frequency not reported: Hyperglycemia, glucosuria[Ref]

Local

Very common (10% or more): Itching (20%), stinging (20%), soreness (20%), burning (20%)[Ref]

Dermatologic

Frequency not reported: Irritation, dryness, folliculitis, hypertrichosis, acneiform eruptions, hypopigmentation, perioral dermatitis, allergic contact dermatitis, maceration of the skin, secondary infection, skin atrophy, striae, miliaria.[Ref]

Some side effects of amcinonide topical may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

Usual Pediatric Dose for Psoriasis

Cream and ointment: Apply a thin film topically to affected area 2 to 3 times a day depending on severity of condition
Lotion: Apply topically and rub into the affected area completely twice a day

Comments:
-Occlusive dressings can be a therapeutic adjunct for the management of psoriasis or recalcitrant conditions.
-If an infection occurs, occlusive dressings should be discontinued and antimicrobial therapy should be initiated.
-The affected area where the drug is applied should be protected from washing, clothing, rubbing until the lotion is dried.
-Administration of topical corticosteroids to pediatric patients should be limited to the least amount compatible with an effective therapeutic regimen.

Uses:
-Relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses

Dialysis

Data not available

Amcinonide topical Pregnancy Warnings

This drug should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. US FDA pregnancy category: C Comments:Topical corticosteroids should not be used extensively on pregnant patients, in large amounts or for extended periods of time.

Animal studies have shown the more potent corticosteroids to be teratogenic after dermal application. There are no adequate and well-controlled studies in pregnant women on the teratogenic effects from topically applied corticosteroids. US FDA pregnancy category C: Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

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