Americaine

Name: Americaine

Uses

This medication is used to relieve pain and itching from certain ear conditions (e.g., middle ear inflammation with congestion and/or fluid build-up, "swimmer's ear", outer ear inflammation). Benzocaine is a topical anesthetic that helps to numb the pain and itching.Do not use this medication in infants younger than 1 year.

Notes

Do not share this medication with others.This medication has been prescribed for your current condition only. Do not use it later for another ear problem unless told to do so by your doctor. A different medication may be necessary in that case.For certain ear problems, it is important to keep the affected ear(s) clean and dry. Try not to get the affected ear(s) wet when bathing. Avoid swimming unless your doctor tells you otherwise. Consult your doctor for more details.

Overdose

No information is available.

What happens if i miss a dose?

Since benzocaine topical is used as needed, you may not be on a dosing schedule. If you are using the medication regularly, use the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.

For the Consumer

Applies to benzocaine topical: cream, film, gel/jelly, gum, liquid, lotion, lozenge/troche, ointment, paste, powder for suspension, solution, spray, swab, tablet disintegrating

Other dosage forms:

  • topical application cream, topical application gel/jelly, topical application liquid, topical application ointment, topical application solution, topical application spray, topical application wax

Along with its needed effects, benzocaine topical (the active ingredient contained in Americaine) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking benzocaine topical:

Incidence not known
  • Headache
  • high fever
  • nausea
  • vomiting
  • worsening of pain, redness, swelling, or irritation in or around the mouth

For Healthcare Professionals

Applies to benzocaine topical: compounding powder, mucous membrane gel, mucous membrane liquid, mucous membrane lozenge, mucous membrane paste, mucous membrane powder for reconstitution, mucous membrane spray, mucous membrane swab, mucous membrane tablet disintegrating, rectal ointment, rectal suppository, topical cream, topical gel, topical liquid, topical lotion, topical ointment, topical spray, topical stick, topical swab

Dermatologic

Dermatologic side effects have included contact dermatitis and urticaria.[Ref]

Local

Local side effects have included burning and stinging.[Ref]

Other

Other side effects have included edema.[Ref]

Cardiovascular

Cardiovascular side effects have included angioedema.

Hematologic

Hematologic side effects have included methemoglobinemia. FDA continues to receive reports of methemoglobinemia from postmarketing reporting.[Ref]

Some side effects of Americaine may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

Usual Adult Dose for Anesthesia

Benzocaine topical 20% mucous membrane spray:
Awake intubation, oral airway, bronchoscopy: Apply 1/2 second burst to buccal folds. Instruct patient to swallow several times. Wait 1 minute, then begin procedure.
Upper endoscopy: Apply 1/2 second burst to each buccal fold and instruct patient to swallow several times. Wait 30 seconds, then insert scope.
Esophageal motility: Apply no longer than 1/2 second burst to each naris. Wait 30 to 60 seconds, then insert transducer.
Indirect laryngoscopy, head and neck examinations: Spray 1/2 second burst to each buccal fold, instruct patient to swallow several times. Wait 30 to 60 seconds before initiating procedure.
Arch bar removal: Spray affected area for no longer than 1/2 second. Wait 30 to 60 seconds, then remove arch bar.
Stomatitis, mucositis, pharyngitis, thrush, cancer of throat: Apply topically to affected area(s) as needed.

Benzocaine topical 20% mucous membrane gel:
Awake intubation, oral airway, bronchoscopy: Apply a small amount to naris prior to nasal intubation.
Proctoscopy, flexible sigmoidoscopy: Apply topically to rectal area, wait 30 to 60 seconds then initiate procedure.
Stomatitis, mucositis, pharyngitis, thrush, cancer of throat: Apply topically to affected area(s) as needed.

Benzocaine topical 20% mucous membrane liquid:
Esophageal motility: Tilt the patient's head back and drip 2 to 3 drops into the naris prior to inserting the transducer.
Indirect laryngoscopy, head and neck examinations: Gargle 1 teaspoonful for approximately 15 seconds, then spit remaining out. Wait 30 to 60 seconds, then initiate procedure.
Nasal biopsies: Tilt patient's head back and drip 2 to 3 drops into each naris. Wait 30 to 60 seconds, then initiate procedure.
Stomatitis, mucositis, pharyngitis, thrush, cancer of throat: Apply topically to affected area(s) as needed.

Benzocaine topical 20% mucous membrane swab:
Nasal biopsies: Apply topically to naris. Wait 30 to 60 seconds, then initiate procedure.

Benzocaine topical 10% to 15% mucous membrane gel: Apply topically to affected area(s) of mouth and gums up to 4 times daily.

Benzocaine topical 10% mucous membrane powder for reconstitution:
Oral mucositis aphthous ulcers, cancer sores, stomatitis, oral lesions and tissue injury caused by ill fitting dentures and gum disease, and oral problems associated with HIV: Apply topically to affected area(s) of mouth and gums every 4 to 6 hours, not to exceed four doses daily.

Benzocaine topical oral lozenge:
Sore throat pain, mouth pain: 1 lozenge dissolved in mouth every 2 hours as needed.

Usual Pediatric Dose for Anesthesia

Greater than or equal to 2 years to 18 years:
Benzocaine topical 10% mucous membrane gel:
Toothache, sore gums, canker sores: Apply topically to affected area(s) up to 4 times daily. A cotton swab may be helpful when applying to young children.

Greater than or equal to 5 years to 18 years:
Benzocaine topical oral lozenge:
Sore throat pain, mouth pain: 1 lozenge dissolved in mouth every 2 hours as needed.

Precautions

Benzocaine topical is considered contraindicated in patients with congenital or idiopathic methemoglobinemia.

Benzocaine should not be used in infants less than 12 months of age who are receiving treatment with methemoglobin- inducing agents.

Benzocaine topical is for external use only, and is not intended to be used in or near the eyes.

Benzocaine crystals may appear as a white precipitate following topical application.

Do not apply in large quantities or over large, raw, or blistered areas,

Benzocaine topical is not intended for use on deep or puncture wounds, or serious burns.

Instruct patients to avoid eating for approximately 1 hour following topical application to oral mucosa.

Safety and effectiveness of benzocaine sore throat lozenges have not been established in children less than 5 years of age.

Benzocaine Identification

Substance Name

Benzocaine

CAS Registry Number

94-09-7

Drug Class

Anesthetics, Local

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