Amoxil

Name: Amoxil

Uses

Amoxicillin is used to treat a wide variety of bacterial infections. This medication is a penicillin-type antibiotic. It works by stopping the growth of bacteria.This antibiotic treats only bacterial infections. It will not work for viral infections (such as common cold, flu). Unnecessary use or misuse of any antibiotic can lead to its decreased effectiveness.Amoxicillin is also used with other medications to treat stomach/intestinal ulcers caused by the bacteria H. pylori and to prevent the ulcers from returning.OTHER This section contains uses of this drug that are not listed in the approved US professional labeling for the drug but that may be prescribed by your health care professional. Use this drug for a condition that is listed in this section only if it has been so prescribed by your health care professional.This drug may also be used by people with certain heart problems (such as heart valve disease) before medical/dental procedures (such as tooth/gum procedures) to prevent heart infection.

Amoxicillin side effects

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with amoxicillin. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.

Common amoxicillin side-effects (these affect less than 1 in 10 people)What can I do if I experience this?
Feeling or being sickStick to simple foods. Try taking your doses of amoxicillin with something to eat if you are not already doing so
DiarrhoeaDrink plenty of water to replace any lost fluids. If the diarrhoea continues, becomes severe, or contains blood, let your doctor know straightaway
Redness and itching in the mouth or vagina (thrush)Speak with your doctor for advice about treatment
Skin rashLet your doctor know as soon as possible as your treatment will need to be changed

Important: if you develop an itchy rash, swollen face or mouth, or have difficulty breathing, these may be signs that you are allergic to a penicillin antibiotic. Do not take any more amoxicillin and speak with your doctor or go to your local accident and emergency department straightaway.

If you experience any other symptoms which you think may be due to the antibiotic, speak with your doctor or pharmacist for further advice.

Warnings

Included as part of the PRECAUTIONS section.

Amoxil Food Interactions

Medicines can interact with certain foods. In some cases, this may be harmful and your doctor may advise you to avoid certain foods. In the case of amoxicillin there are no specific foods that you must exclude from your diet when receiving amoxicillin.

 

Inform MD

Before taking amoxicillin, tell your doctor about all of your medical conditions. Especially tell your doctor if you:

  • are allergic to penicillin or any other medications
  • develop watery and bloody stools (with or without stomach cramps and fever) 2 or more months after having taken the last dose of the antibiotic. This is not typical, and your doctor should be notified.
  • have a history of diarrhea caused by taking antibiotics
  • have phenylketonuria
  • have kidney disease
  • have asthma
  • have hay fever
  • are pregnant or breastfeeding

Tell your doctor about all the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements.

Amoxil Dosage

Take Amoxicillin exactly as prescribed by your doctor. Follow the directions on your prescription label carefully.

The Amoxicillin dose your doctor recommends will be based on the following:

  • the condition being treated
  • other medical conditions you have
  • other medications you are taking
  • how you respond to this medication
  • your weight
  • your height
  • your age
  • your gender

Neonates and Infants aged 12 weeks or younger (≤ 3 months): the recommended upper dose of amoxicillin is 30 mg/kg/day divided and given twice daily.

Adult Dosing (or children 40kg/88 lbs or greater):

  • Ear/Nose/Throat infection, mild or moderate: 500 mg twice daily or 250 mg three times daily
  • Ear/Nose/Throat, severe infection: 875 mg twice daily or 500 mg three times daily
  • Lower respiratory tract (airway) infection, mild or moderate or severe: 875 mg twice daily or 500 mg three times daily
  • Skin/Skin Structure infection, mild or moderate: 500 mg twice daily or 250 mg three times
  • Skin/Skin Structure infection, severe: 875 mg twice daily or 500 mg three times daily
  • Genitourinary tract infection, mild or moderate: 500 mg twice daily or 250 mg three times daily
  • Genitourinary tract infection, severe: 875 mg twice daily or 500 mg three times daily
  • Gonorrhea Acute, uncomplicated ano-genital and urethral infections in males and females: 3 grams as single oral dose

Dosing in Children (greater than 3 months old or less than 40 kg/88 lbs):

  • Ear/Nose/Throat infection, mild or moderate: hours 25 mg/kg/day in divided doses every 12 hours or 20 mg/kg/day in divided doses every 8 hours
  • Ear/Nose/Throat, severe infection: 45 mg/kg/day in divided doses every 12 hours or 40 mg/kg/day in divided doses every 8 hours
  • Lower respiratory tract (airway) infection, mild or moderate or severe: 45 mg/kg/day in divided doses every 12 hours or 40 mg/kg/day in divided doses every 8 hours
  • Skin/Skin Structure infection, mild or moderate: 25 mg/kg/day in divided doses every 12 hours or 20 mg/kg/day in divided doses every 8 hours
  • Skin/Skin Structure infection, severe: 45 mg/kg/day in divided doses every 12 hours or 40 mg/kg/day in divided doses every 8 hours
  • Genitourinary tract infection, mild or moderate: 25 mg/kg/day in divided doses every 12 hours or 20 mg/kg/day in divided doses every 8 hours
  • Genitourinary tract infection, severe: 45 mg/kg/day in divided doses every 12 hours or 40 mg/kg/day in divided doses every 8 hours
  • Gonorrhea Acute, uncomplicated ano-genital and urethral infections in males and females:
    • Prepubertal children: 50 mg/kg amoxicillin, combined with 25 mg/kg probenecid as a single dose. SINCE PROBENECID IS CONTRAINDICATED IN CHILDREN UNDER 2 YEARS, DO NOT USE THIS REGIMEN IN THESE CASES.

Uses For Amoxil

Penicillins are used to treat infections caused by bacteria. They work by killing the bacteria or preventing their growth.

There are several different kinds of penicillins. Each is used to treat different kinds of infections. One kind of penicillin usually may not be used in place of another. In addition, penicillins are used to treat bacterial infections in many different parts of the body. They are sometimes given with other antibacterial medicines (antibiotics). Some of the penicillins may also be used for other problems as determined by your doctor. However, none of the penicillins will work for colds, flu, or other virus infections.

Penicillins are available only with your doctor's prescription.

Overdosage

In case of overdosage, discontinue medication, treat symptomatically, and institute supportive measures as required. If the overdosage is very recent and there is no contraindication, an attempt at emesis or other means of removal of drug from the stomach may be performed. A prospective study of 51 pediatric patients at a poison-control center suggested that overdosages of less than 250 mg/kg of amoxicillin are not associated with significant clinical symptoms and do not require gastric emptying.3

Interstitial nephritis resulting in oliguric renal failure has been reported in a small number of patients after overdosage with amoxicillin.

Crystalluria, in some cases leading to renal failure, has also been reported after amoxicillin overdosage in adult and pediatric patients. In case of overdosage, adequate fluid intake and diuresis should be maintained to reduce the risk of amoxicillin crystalluria.

Renal impairment appears to be reversible with cessation of drug administration. High blood levels may occur more readily in patients with impaired renal function because of decreased renal clearance of amoxicillin. Amoxicillin may be removed from circulation by hemodialysis.

What is amoxicillin (moxatag)?

Amoxicillin is a penicillin antibiotic. It fights bacteria in your body.

Amoxicillin is used to treat many different types of infections caused by bacteria, such as ear infections, bladder infections, pneumonia, gonorrhea, and E. coli or salmonella infection. Amoxicillin is also sometimes used together with another antibiotic called clarithromycin (Biaxin) to treat stomach ulcers caused by Helicobacter pylori infection. This combination is sometimes used with a stomach acid reducer called lansoprazole (Prevacid).

Amoxicillin may also be used for purposes not listed in this medication guide.

For the Consumer

Applies to penicillin v potassium: capsule, powder for solution, powder for suspension, solution, suspension, syrup, tablet, tablet for suspension, tablet chewable, tablet extended release

Along with its needed effects, penicillin v potassium may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Stop taking penicillin v potassium and get emergency help immediately if any of the following effects occur:

Less common
  • Fast or irregular breathing
  • fever
  • joint pain
  • lightheadedness or fainting (sudden)
  • puffiness or swelling around the face
  • red, scaly skin
  • shortness of breath
  • skin rash, hives, itching

Check with your doctor immediately if any of the following side effects occur while taking penicillin v potassium:

Rare
  • Abdominal or stomach cramps and pain (severe)
  • abdominal tenderness
  • convulsions (seizures)
  • decreased amount of urine
  • diarrhea (watery and severe), which may also be bloody
  • mental depression
  • nausea and vomiting
  • pain at place of injection
  • sore throat and fever
  • unusual bleeding or bruising
  • yellow eyes or skin
Rare - For penicillin G procaine only
  • Agitation or combativeness
  • anxiety
  • confusion
  • fear of impending death
  • feeling, hearing, or seeing things that are not real

Some side effects of penicillin v potassium may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common
  • Diarrhea (mild)
  • headache
  • sore mouth or tongue
  • vaginal itching and discharge
  • white patches in the mouth and/or on the tongue

Usual Adult Dose for Fusospirochetosis

250 to 500 mg orally every 6 to 8 hours

Comments:
-For infections involving gum tissue, completion of essential dental care is recommended.

Use: For the treatment of fusospirochetosis (Vincent's gingivitis and pharyngitis), mild to moderately severe infections of the oropharynx

Usual Adult Dose for Anthrax Prophylaxis

US CDC Recommendations: 500 mg orally every 6 hours
Duration of prophylaxis: 60 days

Comments:
-Recommended as an alternative oral regimen for postexposure prophylaxis; recommended for penicillin-susceptible strains
-Current guidelines should be consulted for additional information.

Usual Pediatric Dose for Inhalation Bacillus anthracis

AAP Recommendations:
Up to 1 week of age:
-Gestational age 32 to 37 weeks: 25 mg/kg orally every 12 hours
-Term neonate: 25 mg/kg orally every 8 hours

1 to 4 weeks:
-Gestational age 32 to 37 weeks: 25 mg/kg orally every 8 hours
-Term neonate: 75 mg/kg/day orally in divided doses every 6 to 8 hours

1 month or older: 50 to 75 mg/kg/day orally in divided doses every 6 to 8 hours

Duration of Therapy:
Postexposure prophylaxis for B anthracis infection: 60 days after exposure

Cutaneous anthrax without systemic involvement:
-Bioterrorism-related cases: To complete an antimicrobial regimen of up to 60 days from onset of illness
-Naturally-acquired cases: 7 to 10 days

Follow-up for severe anthrax:
-To complete a regimen of 10 to 14 days or longer (up to 4 weeks of age) or to complete a regimen of 14 days or longer (1 month or older)
-Patients may require prophylaxis to complete an antimicrobial regimen of up to 60 days from onset of illness.

Comments:
-Recommended as an alternative regimen for postexposure prophylaxis, the treatment of cutaneous anthrax without systemic involvement, and oral follow-up therapy for severe anthrax
-Recommended as an alternative for penicillin-susceptible strains
-Recommended for use with a protein synthesis inhibitor when used for follow-up therapy for severe anthrax (includes anthrax meningitis, inhalation anthrax, injection anthrax, gastrointestinal anthrax, and cutaneous anthrax with systemic involvement, extensive edema, or lesions of the head or neck).
-Current guidelines should be consulted for additional information.

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