Amrix

Name: Amrix

Brand names

  • Amrix®
  • Flexeril®

What is cyclobenzaprine (Amrix, Fexmid)?

Cyclobenzaprine is a muscle relaxant.

Why is cyclobenzaprine (Amrix, Fexmid) prescribed to patients?

  • Cyclobenzaprine is used with rest and physical therapy for short-term relief of muscle spasms associated with acute painful muscle and skeletal conditions. It is only for short-term use, up to two or three weeks.

Manufacturer

  • Cephalon, Inc.

Amrix Food Interactions

Medicines can interact with certain foods. In some cases, this may be harmful and your doctor may advise you to avoid certain foods. In the case of Amrix, there are no specific foods that you must exclude from your diet when receiving Amrix.

Alcohol may intensify some of the side effects of this medication.

Amrix and Lactation

Tell your doctor if you are breastfeeding or plan to breastfeed.

It is not known if Amrix is excreted in human breast milk or if it will harm your nursing baby.

How should I take Amrix (cyclobenzaprine)?

Cyclobenzaprine is usually taken once daily for only 2 or 3 weeks. Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.

Take the medicine at the same time each day.

Do not crush, chew, break, or open an extended-release capsule. Swallow it whole.

You may have unpleasant withdrawal symptoms when you stop taking cyclobenzaprine after long-term use. Ask your doctor how to avoid withdrawal symptoms when you stop using this medicine.

Cyclobenzaprine is only part of a complete program of treatment that may also include rest, physical therapy, or other pain relief measures. Follow your doctor's instructions.

Store at room temperature away from moisture, heat, and light.

Amrix (cyclobenzaprine) side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using cyclobenzaprine and call your doctor at once if you have:

  • severe drowsiness, fast heart rate;

  • tremors or shaking;

  • pounding heartbeats or fluttering in your chest; or

  • agitation, hallucinations, fever, overactive reflexes, nausea, vomiting, diarrhea, loss of coordination, fainting.

Common side effects may include:

  • headache, dizziness;

  • drowsiness, tired feeling;

  • trouble concentrating;

  • blurred vision, dry mouth or throat, altered sense of taste; or

  • nausea, upset stomach, constipation.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Amrix (cyclobenzaprine)?

Taking cyclobenzaprine with other drugs that make you sleepy or slow your breathing can cause dangerous or life-threatening side effects. Ask your doctor before taking a sleeping pill, narcotic pain medicine, prescription cough medicine, a muscle relaxer, or medicine for anxiety, depression, or seizures.

This list is not complete. Other drugs may interact with cyclobenzaprine, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.

Uses For Amrix

Cyclobenzaprine is used to help relax certain muscles in your body. It helps relieve pain, stiffness, and discomfort caused by strains, sprains, or injuries to your muscles. However, this medicine does not take the place of rest, exercise or physical therapy, or other treatment that your doctor may recommend for your medical problem. Cyclobenzaprine acts on the central nervous system (CNS) to produce its muscle relaxant effects. Its actions on the CNS may also cause some of this medicine's side effects.

This medicine is available only with your doctor's prescription.

How is this medicine (Amrix) best taken?

Use this medicine as ordered by your doctor. Read all information given to you. Follow all instructions closely.

  • Take with or without food.
  • Take Amrix at the same time of day.
  • Swallow whole. Do not chew or crush.
  • If you cannot swallow this medicine whole, you may sprinkle the contents on applesauce. If you do this, swallow the mixture right away without chewing.
  • Rinse mouth to make sure all contents have been swallowed.
  • Throw away any part not used after use.

What do I do if I miss a dose?

  • Take a missed dose as soon as you think about it.
  • If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
  • Do not take 2 doses at the same time or extra doses.

What are some other side effects of Amrix?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:

  • Feeling sleepy.
  • Dizziness.
  • Dry mouth.
  • Feeling tired or weak.
  • Hard stools (constipation).
  • Upset stomach.

These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.

You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

Drug Interactions

Based on its structural similarity to tricyclic antidepressants, Amrix may have life-threatening interactions with MAO inhibitors [see Contraindications (4)], may enhance the effects of alcohol, barbiturates, and other CNS depressants, may enhance the seizure risk in patients taking tramadol, or may block the antihypertensive action of guanethidine and similarly acting compounds.

Postmarketing cases of serotonin syndrome have been reported during combined use of cyclobenzaprine and other drugs, such as SSRIs, SNRIs, TCAs, tramadol, bupropion, meperidine, verapamil, or MAO inhibitors. [See Warnings and Precautions (5.1)]

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