Analpram HC lotion 2.5%

Name: Analpram HC lotion 2.5%

Description

Analpram HC Cream is a topical preparation containing hydrocortisone acetate 1% or 2.5% w/w and pramoxine hydrochloride 1% w/w in a hydrophilic cream base containing stearic acid, cetyl alcohol, Aquaphor * , isopropyl palmitate, polyoxyl 40 stearate, propylene glycol, potassium sorbate, sorbic acid, triethanolamine lauryl sulfate, and purified water.

Analpram HC Lotion is a topical preparation contain-ing hydrocortisone acetate 2.5% w/w and pramoxine hydro-chloride 1% w/w in a hydrophilic lotion base containing stearic acid, cetyl alcohol, Forlan-L, glycerin, trolamine, polyoxyl 40 stearate, di-isopropyl adipate, povidone, dimethicone, potassium sorbate, sorbic acid, and purified water.

Topical corticosteroids are anti-inflammatory and anti-pruritic agents. The structural formulas, the chemical names, molecular formulas and molecular weights for active ingredients are presented below.

hydrocortisone acetate

Pregn-4-ene-3,20-dione, 21-(acetyloxy)-11,

17-dihydroxy-,(11-beta)-

C 23 H 32 O 6 ; mol. wt. 404.50

pramoxine hydrochloride

4-(3-(p-butoxyphenoxy)propyl)morpholine hydrochloride

C 17 H 27 NO 3 .HCl; mol. wt: 329.87

Contraindications

Topical corticosteroids are contraindicated in those patients with a history of hypersensitivity to any of the components of the preparation.

Overdosage

Topically applied corticosteroids can be absorbed in sufficient amounts to produce systemic effects. (See PRECAUTIONS .)

Dosage and Administration

Topical corticosteroids are generally applied to the affected area as a thin film three to four times daily depending on the severity of the condition. Lotion should be shaken well before use. Occlusive dressings may be used for the management of psoriasis or recalcitrant conditions. If an infection develops, the use of occlusive dressings should be discontinued and appropriate antimicrobial therapy instituted. For cleansing the anogenital area, apply Analpram HC Lotion 2.5% on cotton or tissue and wipe affected area.

(web3)