Aprepitant Oral Suspension

Name: Aprepitant Oral Suspension

What do I need to tell my doctor BEFORE I take Aprepitant Oral Suspension?

  • If you have an allergy to aprepitant or any other part of aprepitant oral suspension.
  • If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
  • If you are taking any of these drugs: Cisapride or pimozide.
  • If you are taking any of these drugs: Clarithromycin, itraconazole, ketoconazole, nefazodone, nelfinavir, ritonavir, or troleandomycin.
  • If you are taking any of these drugs: Carbamazepine, diltiazem, phenytoin, or rifampin.

This is not a list of all drugs or health problems that interact with this medicine.

Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take aprepitant oral suspension with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.

What are some side effects that I need to call my doctor about right away?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

For all uses of this medicine:

  • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
  • A very bad skin reaction (Stevens-Johnson syndrome/toxic epidermal necrolysis) may happen. It can cause very bad health problems that may not go away, and sometimes death. Get medical help right away if you have signs like red, swollen, blistered, or peeling skin (with or without fever); red or irritated eyes; or sores in your mouth, throat, nose, or eyes.

For preventing upset stomach and throwing up from chemo:

  • Signs of infection like fever, chills, very bad sore throat, ear or sinus pain, cough, more sputum or change in color of sputum, pain with passing urine, mouth sores, or wound that will not heal.
  • More thirst.
  • Dry mouth.
  • Dry eyes.

For preventing upset stomach and throwing up from surgery:

  • Very bad dizziness or passing out.

Consumer Information Use and Disclaimer

  • If your symptoms or health problems do not get better or if they become worse, call your doctor.
  • Do not share your drugs with others and do not take anyone else's drugs.
  • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
  • Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
  • Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about this medicine, please talk with your doctor, nurse, pharmacist, or other health care provider.
  • If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

This information should not be used to decide whether or not to take aprepitant oral suspension or any other medicine. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to aprepitant oral suspension. This information is not specific medical advice and does not replace information you receive from the healthcare provider. You must talk with the healthcare provider for complete information about the risks and benefits of using this medicine.

Review Date: October 4, 2017

Highlights for aprepitant

APREPITANT (ap RE pi tant) is used with other medicines to prevent nausea and vomiting caused by cancer treatment (chemotherapy). It is also used alone to prevent nausea and vomiting caused by anesthesia used during surgery.

This drug also comes in other forms, including Oral capsule

This drug can cause serious side effects. See which side effects you should report to your doctor right away.

Know how to use your medication, and learn what might happen if you miss a dose.

Talk to your healthcare provider if you have any of these conditions.

Know what to watch for and get tips for reducing your risks while taking this drug.

Aprepitant May Interact with Other Medications

Do not take this medicine with any of these medicines:

  • cisapride
  • flibanserin
  • lomitapide
  • pimozide

This medicine may also interact with the following medications:

  • diltiazem
  • female hormones, like estrogens or progestins and birth control pills
  • medicines for fungal infections like ketoconazole and itraconazole
  • medicines for HIV
  • medicines for seizures or to control epilepsy like carbamazepine or phenytoin
  • medicines used for sleep or anxiety disorders like alprazolam, diazepam, or midazolam
  • nefazodone
  • paroxetine
  • ranolazine
  • rifampin
  • some chemotherapy medications like etoposide, ifosfamide, vinblastine, vincristine
  • some antibiotics like clarithromycin, erythromycin, troleandomycin
  • steroid medicines like dexamethasone or methylprednisolone
  • tolbutamide
  • warfarin
Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs interact differently in each person, we cannot guarantee that this information includes all possible interactions. This information is not a substitute for medical advice. Always speak with your healthcare provider about possible interactions with all prescription drugs, vitamins, herbs and supplements, and over-the-counter drugs that you are taking.

How to Use aprepitant

Take this medicine by mouth. Follow the directions on the prescription label. Usually, you will take your first dose one hour before your chemotherapy begins, and then once daily in the morning for the next 2 days after your chemotherapy treatment. This medicine may be taken with or without food. Do not take more often than directed.

Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for children as young as 6 months for selected conditions, precautions do apply.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

  • liver disease
  • an unusual or allergic reaction to aprepitant, fosaprepitant, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding
What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What should I watch for while using this medicine?

Do not take this medicine if you already have nausea and vomiting. Ask your health care provider what to do if you already have nausea.

Birth control pills and other methods of hormonal contraception (for example, IUD or patch) may not work properly while you are taking this medicine. Use an extra method of birth control during treatment and for 1 month after your last dose of aprepitant.

This medicine should not be used continuously for a long time.

Visit your doctor or health care professional for regular check-ups. This medicine may change your liver function blood test results.

Where should I keep my medicine?

Keep out of the reach of children.

After this medicine is mixed by your pharmacist, store it in a refrigerator between 2 and 8 degrees C (36 and 46 degrees F). Do not freeze. Throw away any unused medicine after 72 hours. When ready to use, medicine can be kept at room temperature between 20 to 25 degrees C (68 to 77 degrees F) for up to 3 hours.

(web3)