Aspirin and oxycodone
Name: Aspirin and oxycodone
- Aspirin and oxycodone drug
- Aspirin and oxycodone missed dose
- Aspirin and oxycodone side effects
- Aspirin and oxycodone tablet
- Aspirin and oxycodone effects of
- Aspirin and oxycodone dosage
- Aspirin and oxycodone adverse effects
- Aspirin and oxycodone the effects of
How should I take aspirin and oxycodone?
Follow all directions on your prescription label. Oxycodone can slow or stop your breathing. Never use aspirin and oxycodone in larger amounts, or for longer than prescribed. Tell your doctor if the medicine seems to stop working as well in relieving your pain.
Oxycodone may be habit-forming, even at regular doses. Never share this medicine with another person, especially someone with a history of drug abuse or addiction. MISUSE OF NARCOTIC MEDICINE CAN CAUSE ADDICTION, OVERDOSE, OR DEATH, especially in a child or other person using the medicine without a prescription. Selling or giving away aspirin and oxycodone is against the law.
Aspirin and oxycodone may be taken with food if it upsets your stomach.
If you need surgery, tell the surgeon ahead of time that you are using aspirin and oxycodone. You may need to stop using the medicine for a short time.
Do not stop using aspirin and oxycodone suddenly after long-term use, or you could have unpleasant withdrawal symptoms. Ask your doctor how to safely stop using this medicine.
Store at room temperature away from moisture, heat, and light. Keep track of the amount of medicine used from each new bottle. Oxycodone is a drug of abuse and you should be aware if anyone is using your medicine improperly or without a prescription.
Do not keep unused aspirin and oxycodone that is no longer needed. Ask your pharmacist where to locate a community drug take-back disposal program. If there is no take-back program, flush any unused medicine down the toilet.
What happens if I miss a dose?
Since aspirin and oxycodone is used for pain, you are not likely to miss a dose. Skip any missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
For the Consumer
Applies to aspirin / oxycodone: oral tablet
Along with its needed effects, aspirin / oxycodone may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking aspirin / oxycodone:
Incidence not known- Abdominal pain, cramping, or tenderness
- agitation
- bleeding gums
- bloating
- blood in the urine or stools
- bloody, black, or tarry stools
- blue lips, fingernails, or skin
- blurred vision
- burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
- change in consciousness or confusion
- chest pain or discomfort
- chills
- clay-colored stools
- constipation
- convulsions
- coughing or vomiting blood
- dark-colored urine
- decrease in urine volume or frequency
- decreased appetite
- depression
- difficult, fast, noisy breathing, sometimes with wheezing
- difficulty in passing urine (dribbling)
- dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
- drowsiness
- dry mouth
- fainting
- fast, slow, irregular, pounding, or racing heartbeat or pulse
- feeling of hostility or irritability
- feeling of warmth
- feeling that something terrible will happen
- fever
- headache, sudden, severe
- heartburn
- hives, itching, or skin rash
- increased menstrual flow or vaginal bleeding
- increased sweating
- indigestion
- irregular, fast, slow, or shallow breathing
- large, flat, blue or purplish patches in the skin
- large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
- loss of consciousness
- muscle cramping, weakness, or tremors
- muscle pain or stiffness
- nausea or vomiting
- nosebleeds
- numbness or tingling in the hands, feet, or lips
- painful or difficult urination
- pains in the stomach, side, or abdomen, possibly radiating to the back
- pale skin
- pinpoint red or purple spots on the skin
- prolonged bleeding from cuts
- puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
- red or black, tarry stools or dark urine
- restlessness
- shivering
- sleepiness
- sunken eyes
- sweating
- swelling of face, ankles, hands, feet, or lower legs
- thirst
- tightness in the chest
- unusual bleeding or bruising
- unusual tiredness or weakness
- vomiting of material that looks like coffee grounds, severe and continuing
- weak or feeble pulse
- weakness or heaviness of the legs
- weight gain
- wrinkled skin
- yellow eyes or skin
Get emergency help immediately if any of the following symptoms of overdose occur while taking aspirin / oxycodone:
Symptoms of overdose- Continuing ringing or buzzing or other unexplained noise in the ears
- decreased awareness or responsiveness
- diarrhea
- drowsiness
- enlarged pupils
- extremely high fever or body temperature
- fast, weak heartbeat
- hearing loss
- increase in heart rate
- restlessness
- severe sleepiness
Some side effects of aspirin / oxycodone may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More common- Relaxed and calm feeling
- sleepiness
- Belching
- bloated, full feeling
- blurred or loss of vision
- change in color perception
- cold sweats
- constricted, pinpoint, or small pupils (black part of the eye)
- cool, pale skin
- double vision
- excess air or gas in the stomach
- false or unusual sense of well-being
- flushed, dry skin
- fruit-like breath odor
- halos around lights
- increased hunger or thirst
- increased urination
- lack or loss of strength
- night blindness
- nightmares
- overbright appearance of lights
- red eyes
- redness of the skin
- seeing, hearing, or feeling things that are not there
- shakiness
- sleepiness or unusual drowsiness
- slurred speech
- trouble sleeping
- tunnel vision
- unusual drowsiness, dullness, tiredness, weakness, or feeling of sluggishness
- weight loss
For Healthcare Professionals
Applies to aspirin / oxycodone: oral tablet
General
The most commonly reported adverse events have included lightheadedness, dizziness, drowsiness, sedation, nausea, and vomiting.[Ref]
Gastrointestinal
Oxycodone-Aspirin:
Frequency not reported: Nausea, vomiting, constipation
Postmarketing reports: Hemorrhagic gastric/duodenal ulcer, gastric/peptic ulcer, dyspepsia, abdominal pain, diarrhea, eructation, dry mouth, gastrointestinal bleeding, intestinal perforation, pancreatitis, intestinal obstruction, ileus, thirst, aspiration
Aspirin:
Frequency not reported: Anorexia[Ref]
Nervous system
Frequency not reported: Lightheadedness, dizziness, drowsiness, sedation
Postmarketing reports: Stupor, paresthesia, cerebral edema, coma, subdural or intracranial hemorrhage, seizures
Opioids:
Postmarketing reports: Serotonin syndrome[Ref]
Renal
Postmarketing reports: Renal insufficiency and failure[Ref]
Hematologic
Oxycodone-aspirin:
Postmarketing reports: Unspecified hemorrhage, purpura, reticulocytosis, prolongation of prothrombin time, disseminated intravascular coagulation, ecchymosis, thrombocytopenia
Aspirin:
Frequency not reported: Leukopenia, thrombocytopenia, purpura, decreased iron concentration, shortened erythrocyte survival time[Ref]
Hypersensitivity
Postmarketing reports: Anaphylaxis, allergic reaction, angioedema[Ref]
Cardiovascular
Frequency not reported: Hypotension
Postmarketing reports: Tachycardia, dysrhythmias, orthostatic hypotension, bradycardia, palpitations[Ref]
Metabolic
Postmarketing reports: Hypoglycemia, hyperglycemia, acidosis, alkalosis, dehydration, hyperkalemia[Ref]
Other
Postmarketing reports: Malaise, asthenia, hypothermia, accidental overdose, non-accidental overdose, hearing loss, tinnitus[Ref]
Hepatic
Oxycodone-aspirin:
Postmarketing reports: Transient elevations of hepatic enzymes, hepatitis, Reye syndrome
Aspirin:
Frequency not reported: Reversible hepatotoxicity[Ref]
Psychiatric
Frequency not reported: Euphoria, dysphoria
Postmarketing reports: Agitation, confusion, anxiety, mental impairment, drug dependence, drug abuse, depression, nervousness, hallucination[Ref]
Dermatologic
Frequency not reported: Pruritus
Postmarketing reports: Urticaria, rash, flushing, increased sweating[Ref]
Musculoskeletal
Postmarketing reports: Rhabdomyolysis
Ocular
Postmarketing reports: Miosis, visual disturbances, red eye
Genitourinary
Frequency not reported: Urinary retention, interstitial nephritis, proteinuria
Respiratory
Frequency not reported: Apnea, respiratory arrest, respiratory depression
Postmarketing reports: Bronchospasm, dyspnea, hyperpnea, pulmonary edema, tachypnea, hypoventilation, laryngeal edema
Endocrine
Adrenal insufficiency and androgen deficiency have been reported with opioid use, most often with chronic use.
Opioids:
Postmarketing reports: Adrenal insufficiency, androgen deficiency
Some side effects of aspirin / oxycodone may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.
Aspirin / oxycodone Breastfeeding Warnings
Not recommended Excreted into human milk: Yes Comments: -If used, monitor breastfed infants for excess sedation and respiratory depression. -Withdrawal symptoms may occur in breastfed infants when maternal administration of an opioid is stopped or when breast-feeding is stopped.
Maternal use of narcotics during breastfeeding can cause infant drowsiness, central nervous system depression, and even death. Infant sedation is common with maternal use of oxycodone. Newborn infants are particularly sensitive to the effects of even small dosages of narcotic analgesics. Adverse effects on platelet function are possible when nursing infants are exposed to aspirin; the risk of Reye Syndrome caused by salicylate in breast milk is unknown.