Atropine Ophthalmic Solution
Name: Atropine Ophthalmic Solution
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Hypersensitivity to any Component of this Medication
Atropine sulfate ophthalmic solution should not be used in anyone who has demonstrated a previous hypersensitivity or known allergic reaction to any ingredient of the formulation because it may recur.
Warnings and precautions
Photophobia and Blurred Vision
Photophobia and blurred vision due to pupil unresponsiveness and cycloplegia may last up to 2 weeks.
Elevation of Blood Pressure
Elevations in blood pressure from systemic absorption has been reported following conjunctival instillation of recommended doses of atropine sulfate ophthalmic solution, USP 1%.
The following serious adverse reactions are described below and elsewhere in the labeling:
- Photophobia and Blurred Vision [See Warnings and Precautions (5.1)]
- Elevation in Blood Pressure [See Warnings and Precautions (5.2)]
The following adverse reactions have been identified following use of atropine sulfate ophthalmic solution. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure.
Ocular Adverse Reactions
Eye pain and stinging occurs upon instillation of atropine sulfate ophthalmic solution. Other commonly occurring adverse reactions include, blurred vision, photophobia, superficial keratitis and decreased lacrimation. Allergic reactions such as papillary conjunctivitis, contact dermatitis, and lid edema may also occur less commonly.
Systemic Adverse Reactions
Systemic effects of atropine are related to its anti-muscarinic activity. Systemic adverse events reported include dryness of skin, mouth, and throat from decreased secretions from mucus membranes; restlessness, irritability or delirium from stimulation of the central nervous system; tachycardia; flushed skin of the face and neck.
Monoamine oxidase inhibitors (MAOI)
The use of atropine and monoamine oxidase inhibitors (MAOI) is generally not recommended because of the potential to precipitate hypertensive crisis.
Highlights for atropine
ATROPINE (A troe peen) can dilate your pupils before examinations and can treat different eye problems.
This drug also comes in other forms, including Injectable solution, Oral tablet, Ophthalmic ointment
This drug can cause serious side effects. See which side effects you should report to your doctor right away.
Know how to use your medication, and learn what might happen if you miss a dose.
Talk to your healthcare provider if you have any of these conditions.
Know what to watch for and get tips for reducing your risks while taking this drug.
Atropine May Interact with Other Medications
Interactions are not expected. Do not use any other eye products without asking your doctor or health care professional.Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs interact differently in each person, we cannot guarantee that this information includes all possible interactions. This information is not a substitute for medical advice. Always speak with your healthcare provider about possible interactions with all prescription drugs, vitamins, herbs and supplements, and over-the-counter drugs that you are taking.