Atrovent

Name: Atrovent

Interactions for Atrovent

Limited systemic absorption following oral inhalation; interactions with systemically administered drugs unlikely.2 190 191

Specific Drugs

Drug

Interaction

Comments

Antimuscarinic agents

Potential pharmacodynamic interaction (additive effects)1 320

Caution advised with concomitant administration1

Methylxanthine derivatives

No adverse drug interactions reported115 120 121 132 157 158 149 187 220 261 305 329

β-Adrenergic agonists

Potential pharmacodynamic interaction (additive effects)4 6 133 147 152 155 225 228 246 248 260 262 278 279 285 287 288 289

If concomitant therapy is required, consider cautious use of cardioselective β-adrenergic blocking agents115 132 139 146 153 154 181 216

Corticosteroids

No adverse drug interactions reported91 115 119 120 121 124 132 153 154 160 329

Cromolyn sodium

No adverse drug interactions reported132 159

What happens if I miss a dose?

Use the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.

What other drugs will affect Atrovent?

Tell your doctor about all medicines you use, and those you start or stop using during your treatment with Atrovent, especially:

  • bladder or urinary medicine such as darifenacin, fesoterodine, oxybutynin, tolterodine, or solfenacin;

  • other bronchodilators such as tiotropium;

  • cold or allergy medicine that contains an antihistamine;

  • medication for Parkinson's disease; or

  • medication to treat excess stomach acid, stomach ulcer, motion sickness, or irritable bowel syndrome.

This list is not complete. Other drugs may interact with Atrovent, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.

For Healthcare Professionals

Applies to ipratropium: compounding powder, inhalation aerosol, inhalation solution

General

The most common adverse reactions were bronchitis, COPD exacerbation, dyspnea, headache, throat irritation, cough, dry mouth, gastro-intestinal motility disorders (including constipation, diarrhea and vomiting), nausea, and dizziness.[Ref]

Respiratory

Very common (10% or more): Bronchitis (up to 14.6%), upper respiratory tract infection (up to 13.2%)
Common (1% to 10%): Chest pain, cough, dyspnea, bronchospasm, sputum increased, pharyngitis, rhinitis, sinusitis, throat irritation
Uncommon (0.1% to 1%): Paradoxical bronchospasm, laryngospasm, pharyngeal edema, dry throat[Ref]

Gastrointestinal

Common (1% to 10%): Mouth dryness, nausea, gastrointestinal motility disorder, dyspepsia
Uncommon (0.1% to 1%): Constipation, diarrhea, taste perversion, vomiting, stomatitis
Frequency not reported: Mouth edema[Ref]

Genitourinary

Common (1% to 10%): Urinary tract infection
Uncommon (0.1% to 1%): Urinary retention[Ref]

Musculoskeletal

Common (1% to 10%): Back pain
Uncommon (0.1% to 1%): Arthritis[Ref]

Nervous system

Common (1% to 10%): Headache, dizziness
Uncommon (0.1% to 1%): Tremor, nervousness[Ref]

Other

Common (1% to 10%): Influenza-like symptoms, pain[Ref]

Cardiovascular

Uncommon (0.1% to 1%): Hypertension, palpitations, supraventricular tachycardia
Rare (less than 0.1%): Atrial fibrillation, rate increased
Frequency not reported: Hypotension, palpitation, tachycardia[Ref]

Dermatologic

Uncommon (0.1% to 1%): Rash, pruritus
Rare (less than 0.1%): Urticaria[Ref]

Hypersensitivity

Uncommon (0.1% to 1%): Hypersensitivity, anaphylactic reactions, angioedema of tongue, lips, face
Frequency not reported: Urticaria (including giant urticaria), laryngospasm[Ref]

Ocular

Uncommon (0.1% to 1%): Blurred vision, mydriasis, intraocular pressure increased, glaucoma, eye pain, halo vision, conjunctival hyperemia, corneal edema
Rare (less than 0.1%): Accommodation disorder
Frequency not reported: Precipitation or worsening of narrow-angle glaucoma, acute eye pain[Ref]

Some side effects of Atrovent may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

Atrovent Side Effects

More Common Side Effects

Some of the more common side effects of Atrovent include:

  • headache

  • upper respiratory tract infection, such as the common cold

  • nosebleeds

  • nasal dryness

  • nasal irritation

  • pharyngitis (sore throat)

If these effects are mild, they may go away within a few days or a couple of weeks. If they’re more severe or don’t go away, talk to your doctor or pharmacist.

Serious Side Effects

Call your doctor right away if you have serious side effects. Call 9-1-1 if your symptoms feel life-threatening or if you think you’re having a medical emergency. Serious side effects and their symptoms can include the following:

  • allergic reactions. Symptoms can include:

    • itching
    • skin rash
    • hives
    • swelling of your lips, tongue, throat, or face
    • trouble breathing or swallowing
  • eye pain

  • blurred vision

Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs affect each person differently, we cannot guarantee that this information includes all possible side effects. This information is not a substitute for medical advice. Always discuss possible side effects with a healthcare provider who knows your medical history.

How to Take Atrovent (Dosage)

All possible dosages and drug forms may not be included here. Your dosage, drug form, and how often you take the drug will depend on:

  • your age
  • the condition being treated
  • how severe your condition is
  • other medical conditions you have
  • how you react to the first dose

What are you taking this medication for?

Rhinorrhea (runny nose)

Brand: Atrovent

Form: Nasal spray Strengths: 0.03%, 0.06%

0.03% nasal spray:

Adult dosage (ages 18 years and older)

Runny nose due to allergic or nonallergic rhinitis: The usual dose is 2 sprays per nostril given 2–3 times per day.

Child dosage (ages 6–17 years)

Runny nose due to allergic or nonallergic rhinitis: The usual dose is 2 sprays per nostril given 2–3 times per day.

Child dosage (ages 0–5 years)

Runny nose due to allergic or nonallergic rhinitis: This drug hasn’t been studied in children younger than 6 years old and shouldn’t be used in children younger than 6 years old.

0.06% nasal spray:

Adult dosage (ages 18 years and older)
  • Runny nose due to allergic rhinitis: The usual dose is 2 sprays per nostril given four times per day.
  • Runny nose due to the common cold: The usual dose is 2 sprays per nostril given 3–4 times per day.
Child dosage (ages 12–17 years)
  • Runny nose due to allergic rhinitis: The usual dose is 2 sprays per nostril given four times per day.
  • Runny nose due to the common cold: The usual dose is 2 sprays per nostril given 3–4 times per day.
Child dosage (ages 5–11 years)
  • Runny nose due to allergic rhinitis: The usual dose is 2 sprays per nostril given four times per day.
  • Runny nose due to the common cold: The usual dose is 2 sprays per nostril given three times per day.
Child dosage (ages 0–4 years)

This drug hasn’t been studied in children and shouldn’t be used in children younger than 5 years old.

Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs affect each person differently, we cannot guarantee that this list includes all possible dosages. This information is not a substitute for medical advice. Always to speak with your doctor or pharmacist about dosages that are right for you. Important considerations for taking this drug

Store this drug at room temperature

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A prescription for this medication is refillable

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Travel

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Self-management

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Are there any alternatives?

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