Name: Avage

What should I do if I forget a dose?

If you are using tazarotene gel, skip the missed dose and continue your regular dosing schedule.

If you are using tazarotene cream or foam, apply the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule.

Do not apply extra gel, cream or foam at the next scheduled dose to make up for a missed dose.

US Brand Name

  1. Avage
  2. Fabior
  3. Tazorac

Patient Handout

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(To understand fully the indication for this product, please read the entire INDICATIONS AND USAGE section of the labeling.)

AVAGE® (TAZAROTENE) Cream 0.1% is indicated as an adjunctive agent for use in the mitigation (palliation) of facial fine wrinkling, facial mottled hyper- and hypopigmentation, and benign facial lentigines in patients who use comprehensive skin care and sunlight avoidance programs. AVAGE® (TAZAROTENE) Cream 0.1% DOES NOT ELIMINATE or PREVENT WRINKLES, REPAIR SUNDAMAGED SKIN, REVERSE PHOTOAGING, or RESTORE MORE YOUTHFUL or YOUNGER SKIN.

  • AVAGE® (TAZAROTENE) Cream 0.1% has NOT DEMONSTRATED A MITIGATING EFFECT on significant signs of chronic sunlight exposure such as coarse or deep wrinkling, tactile roughness, telangiectasia, skin laxity, keratinocytic atypia, melanocytic atypia, or dermal elastosis.
  • AVAGE® (TAZAROTENE) Cream 0.1% should be used under medical supervision as an adjunct to a comprehensive skin care and sunlight avoidance program that includes the use of effective sunscreens (minimum SPF of 15) and protective clothing.
  • Neither the safety nor the effectiveness of AVAGE® (TAZAROTENE) Cream 0.1% for the prevention or treatment of actinic keratoses, skin neoplasms, or lentigo maligna has been established.
  • Neither the safety nor the efficacy of using AVAGE® (TAZAROTENE) Cream 0.1% daily for greater than 52 weeks has been established, and daily use beyond 52 weeks has not been systematically and histologically investigated in adequate and wellcontrolled trials. (See WARNINGS section.)

Uses of Avage

Avage is a prescription medication used to treat fine facial wrinkles and over and underpigmenting of the facial skin in people who use comprehensive skin care and sunlight avoidance programs. It does not eliminate or prevent wrinkles, repair sun-damaged skin, reverse photo aging, or restore more youthful or younger skin.

This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information.

Avage Precautions

Serious side effects have been reported with Avage including the following:

  • Severe irritation. Avoid using Avage on areas of skin that have eczema.
  • Sunburn. Avoid excess sun exposure, wear protective clothing, and wear sunscreen while using Avage.

Do not take Avage if you:

  • are allergic to Avage or to any of its ingredients
  • are pregnant or planning to become pregnant soon

Avage Food Interactions

Medications can interact with certain foods. In some cases, this may be harmful and your doctor may advise you to avoid certain foods. In the case of Avage, there are no specific foods that you must exclude from your diet when receiving this medication.

Avage and Pregnancy

Tell your doctor if you are pregnant or plan to become pregnant.

The FDA categorizes medications based on safety for use during pregnancy. Five categories - A, B, C, D, and X, are used to classify the possible risks to an unborn baby when a medication is taken during pregnancy.

Avage falls into category X. It has been shown that women taking Avage during pregnancy may have babies born with problems. There are no situations where the benefits of the medication for the mother outweigh the risks of harm to the baby. These medicines should never be used by pregnant women.

Other Requirements

Store at 25°C (77°F).
Excursions permitted from -5° to 30°C (23° to 86°F).

What are some side effects that I need to call my doctor about right away?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

  • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
  • Skin irritation.
  • Itching.
  • Burning.
  • Redness.
  • Peeling.
  • Sunburn.
  • Swelling.


Avage Cream is contraindicated in :

  • Pregnancy. Retinoids may cause fetal harm when administered to a pregnant female [see Warnings and Precautions (5.1), Use in Specific Populations (8.1, 8.3)].
  • Individuals who have known hypersensitivity to any of its components [see Warnings and Precautions (5.2)].


Avage Cream is not for oral use. Oral ingestion of the drug may lead to the same adverse effects as those associated with excessive oral intake of Vitamin A (hypervitaminosis A) or other retinoids. . If oral ingestion occurs, monitor the patient closely and administer appropriate supportive measures, as necessary.

Other Interactions

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

What is tazarotene topical (avage, fabior, tazorac)?

Tazarotene is a compound similar to vitamin A. It helps the skin to renew itself more quickly and may improve the appearance and texture of skin.

The Avage brand of tazarotene cream is used to reduce the appearance of fine wrinkles on the face, mottled light and dark skin patches on the face, and benign facial lentigines (non-cancerous freckles) in adults and adolescents who are at least 17 years old.

The Fabior and Tazorac brands of tazarotene topical are used to treat acne vulgaris in adults and adolescents who are at least 12 years old.

Tazorac is also used to treat plaque psoriasis (raised, silvery flaking of the skin) in adults.

Tazarotene topical may also be used for purposes not listed in this medication guide.

What should i discuss with my healthcare provider before using tazarotene topical (avage, fabior, tazorac)?

You should not use tazarotene topical if you are allergic to it, or if you are pregnant or may become pregnant.

To make sure you can safely use tazarotene topical, tell your doctor if you have any of these other conditions:

  • eczema, sunburn, or another skin condition;
  • a personal or family history of skin cancer;
  • lentigo maligna (a type of skin cancer);
  • a history of allergic reaction to a skin product;
  • if you are sensitive to sunlight; or
  • if you work outdoors.

FDA pregnancy category X. This medication can harm an unborn baby or cause birth defects. Do not use tazarotene topical if you are pregnant. Tell your doctor if you are pregnant or plan to become pregnant while using tazarotene topical.

You must have a negative pregnancy test within 2 weeks before starting this treatment. Use effective birth control while using tazarotene topical.

Stop using this medication and tell your doctor right away if you become pregnant, if you stop using birth control, or if you miss a menstrual period.

It is not known whether tazarotene topical passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

  • Wrinkles