Azficel-t Intradermal

Name: Azficel-t Intradermal

Commonly used brand name(s)

In the U.S.

  • Laviv

Available Dosage Forms:

  • Suspension

Proper Use of azficel-t

A trained doctor will give you azficel-t in a hospital or clinic. azficel-t is given through a small needle placed into your nasolabial fold wrinkles.

Your doctor will take three small skin samples (called biopsies) from behind your ears and send them to the manufacturer. Certain cells are grown from these samples for 3 to 6 months.

The processed cells (Laviv®) are shipped back by the manufacturer to your doctor. Your doctor will check and confirm if it came from your own skin. Then, your doctor will inject your medicine into the nasolabial fold wrinkles.

azficel-t is usually given in 3 doses, spaced 3 to 6 weeks apart.

After treatment with azficel-t:

  • Apply a cold compress for 2 to 3 minutes at a time if needed to ease swelling or discomfort. Do not apply ice directly to the face.
  • Do not wash the injection site for at least 24 hours.
  • Do not rub, scrub, or massage the injection site for at least 72 hours.
  • Do not apply any cosmetic products (e.g., make-up, facial creams, or sunscreen) to the treatment area for 72 hours.

It is very important that you receive all doses of azficel-t. Try to keep all scheduled appointments. If you miss a dose, your medicine will not be usable. Your doctor will work with you to schedule a new appointment for the skin collection or biopsy. You may also get a new appointment for your injection.

azficel-t usually comes with a patient information leaflet. Read the information carefully and make sure you understand them before receiving azficel-t. If you have any questions, ask your doctor.

Precautions While Using azficel-t

It is very important that your doctor check your progress at regular visits to make sure that azficel-T is working properly and to check for unwanted effects.

Laviv® is made especially for you from your own skin cells. Do not use someone else's skin cells because it may cause a serious reaction. Do not let anyone use your medicine.

azficel-t may cause serious types of allergic reaction, including anaphylaxis. Anaphylaxis can be life-threatening and requires immediate medical attention. Call your doctor right away if you have a rash; itching; hoarseness; trouble with breathing; trouble with swallowing; or any swelling of your hands, face, or mouth while you are receiving azficel-t.

azficel-t may increase your risk of bleeding or bruising at the injection site. Check with your doctor right away if you have large, flat, blue, or purplish patches in the skin; or unusual bleeding or bruising after receiving Laviv®. Make sure your doctor knows if you are taking aspirin, pain or arthritis medicine called NSAIDs (such as celecoxib, ibuprofen, naproxen, rofecoxib, valdecoxib, Advil®, Aleve®, Bextra®, Celebrex®, Motrin®, or Vioxx®), or a blood thinner (such as warfarin, Coumadin®).

Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.

Azficel-T Identification

Substance Name

Azficel-T

Drug Class

Tissue Therapy

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