Bacitracin and Polymyxin B (Topical)

Name: Bacitracin and Polymyxin B (Topical)

Index Terms

  • Bacitracin Zinc/Polymyx B Sulfate
  • Bacitracin/Polymyxin B Sulfate
  • Polymyxin B and Bacitracin

Brand Names U.S.

  • Double Antibiotic [OTC]
  • Polysporin [OTC]


See individual agents.


Insignificant from intact skin or mucous membrane


Hypersensitivity to bacitracin, polymyxin B, or any component of the formulation

Dosing Adult

Topical infection prevention: Topical: Apply to affected area 1 to 3 times/day; may cover with sterile bandage if needed.

What are some other side effects of this drug?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:

  • Burning.
  • Itching.

These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.

You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at

Some side effects of bacitracin / polymyxin b topical may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.