Bacitracin Zinc topical

Name: Bacitracin Zinc topical

Bacitracin Zinc Dosage and Administration

Administration

Apply ointment or powder topically to cleansed area.a

May cover affected area with a sterile bandage following use of ointments, powders, or sprays.a

Has been used for topical compresses in 0.9% sodium chloride injection or sterile water for injection (250–1000 units/mL).a

Dosage

Adults

Superficial Skin Infections Topical

Ointment: Apply amount equal to the surface area of a fingertip to the affected area 1–3 times daily.a

Powder: Use a light dusting on affected area 1–3 times daily.a

Prescribing Limits

Maximum 1 week of use unless directed by a physician.a

Cautions for Bacitracin Zinc

Contraindications

  • Known history of hypersensitivity to bacitracin or any ingredients in the formulations.a

  • Avoid use in atopic individuals.a

Warnings/Precautions

Sensitivity Reactions

Rashes and allergic anaphylactoid reactions have occurred, but topical application has low order of toxicity.a

If itching, burning, inflammation, or other signs of sensitivity occur, discontinue use and consult a clinician.a

Sensitivity to neomycin also may indicate sensitivity to bacitracin.a

Patch testing (e.g., 1% bacitracin in petrolatum) may be useful in diagnosing suspected allergic contact dermatitis when hypersensitivity to other topical antibiotics (e.g., neomycin) is suspected.a

General Precautions

Overgrowth of nonsusceptible organisms, particularly Candida, may occur; institute appropriate therapy if superinfection occurs.a

Topical use of bacitracin should not replace appropriate surgical management or other measures.a

Consider systemic anti-infective therapy if a deep-seated infection is present.a

Corticosteroids in topical anti-infective combination preparations may mask the clinical signs of bacterial, fungal, or viral infections, or may suppress hypersensitivity reactions to the antibiotics or other ingredients in the formulations; weigh benefits against risks.a

Use of Fixed Combination

When used in fixed combination with other agents, consider the cautions, precautions, and contraindications associated with the concomitant agents.

Specific Populations

Pregnancy

Category C.b

Lactation

Not known whether topical bacitracin is distributed into milk.b

Preparations

Excipients in commercially available drug preparations may have clinically important effects in some individuals; consult specific product labeling for details.

Please refer to the ASHP Drug Shortages Resource Center for information on shortages of one or more of these preparations.

* available from one or more manufacturer, distributor, and/or repackager by generic (nonproprietary) name

Bacitracin

Routes

Dosage Forms

Strengths

Brand Names

Manufacturer

Bulk

Powder*

Topical

Ointment

500 units/g*

Baciguent

Lee Pharmaceuticals

* available from one or more manufacturer, distributor, and/or repackager by generic (nonproprietary) name

Bacitracin Combinations

Routes

Dosage Forms

Strengths

Brand Names

Manufacturer

Topical

Ointment

400 units/g with Neomycin Sulfate 0.5% (0.35% of neomycin) and Polymyxin B Sulfate 5000 units (of polymyxin B) per g*

Triple Antibiotic Ointment

Alpharma, Pfeiffer

Bacitracin Zinc

Routes

Dosage Forms

Strengths

Brand Names

Manufacturer

Bulk

Powder

Topical

Ointment

500 units (of bacitracin) per g

Bacitracin Zinc Ointment

Alpharma, Rugby

* available from one or more manufacturer, distributor, and/or repackager by generic (nonproprietary) name

Bacitracin Zinc Combinations

Routes

Dosage Forms

Strengths

Brand Names

Manufacturer

Topical

Ointment

400 units (of bacitracin) per g with Neomycin Sulfate 0.5% (0.35% of neomycin) and Polymyxin B Sulfate 5000 units (of polymyxin B) per g

Neosporin

Pfizer

Triple Antibiotic Ointment

500 units (of bacitracin) per g with Lidocaine 4%, Neomycin Sulfate 0.5% (0.35% of neomycin), and Polymyxin B Sulfate 10,000 units (of polymyxin B) per g*

Bactine First Aid Antibiotic Plus Anesthetic

Bayer

Campho-Phenique First Aid Antibiotic Plus Pain Reliever Maximum Strength

Bayer

Mycitracin Plus Pain Reliever (with parabens)

J&J Consumer

Spectrocin Plus

Numark

Triple Antibiotic Extra

IVAX

Triple Antibiotic Plus Ointment Maximum Strength

Alpharma, G&W, Major

Triple Antibiotic with Lidocaine Ointment Maximum Strength

Clay-Park, Moore

500 units (of bacitracin) per g with Neomycin Sulfate 0.5% (0.35% of neomycin) and Polymyxin B Sulfate 10,000 units (of polymyxin B) per g

Mycitracin Triple Antibiotic First Aid Ointment Maximum Strength (with parabens)

J&J Consumer

500 units (of bacitracin) per g with Polymyxin B Sulfate 10,000 units (of polymyxin B) per g and Pramoxine Hydrochloride 1%

Betadine Brand First Aid Antibiotics + Pain Reliever

Purdue Frederick

500 units (of bacitracin) per g, with Neomycin Sulfate 0.5% (0.35% of neomycin), Polymyxin B Sulfate 10,000 units (of polymyxin B) per g, and Pramoxine Hydrochloride 1%

Neosporin Plus Maximum Strength First Aid Antibiotic/Pain Relieving Ointment

Pfizer

500 units (of bacitracin) per g with Polymyxin B Sulfate 10,000 units (of polymyxin B) per g

Bacitracin-Polymyxin Ointment

Clay-Park, Major, Rugby

Band-Aid with Antibiotic Ointment

J&J Consumer

Betadine Brand First Aid Antibiotics + Moisturizer Ointment

Purdue Frederick

Double Antibiotic Ointment

Fougera

Polysporin Ointment

Pfizer

Powder

500 units (of bacitracin) per g with Polymyxin B Sulfate 10,000 units (of polymyxin B) per g

Polysporin Powder

Pfizer

Anti-infective combinations including bacitracin are also commercially available in combination with corticosteroids for topical use.

Side Effects

This medication usually has no side effects. If you have any unusual effects, contact your doctor or pharmacist promptly.

If your doctor has directed you to use this medication, remember that he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Rarely, use of this medication for prolonged or repeated periods may result in other types of skin infections (such as fungal or other bacterial infections). Contact your doctor if you notice any unusual skin symptoms or if your condition does not improve.

A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

List Bacitracin Zinc Ointment side effects by likelihood and severity.

Precautions

Before using bacitracin, tell your doctor or pharmacist if you are allergic to it; or to neomycin; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history.

Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.

It is unknown if this medication passes into breast milk. Consult your doctor before breast-feeding.

Overdose

This medicine may be harmful if swallowed. If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center.

Notes

Keep all regular medical and laboratory appointments.

Missed Dose

If you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.

Storage

Store at room temperature between 59-86 degrees F (15-30 degrees C). Different forms of this medication may have different storage requirements. Read the package labeling or ask your pharmacist for the storage requirements for the product you are using. Keep all medications away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details about how to safely discard your product.Information last revised July 2016. Copyright(c) 2016 First Databank, Inc.

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