Belatacept Intravenous

Name: Belatacept Intravenous

Commonly used brand name(s)

In the U.S.

  • Nulojix

Available Dosage Forms:

  • Powder for Solution

Therapeutic Class: Immunological Agent

Uses For belatacept

Belatacept injection belongs to a group of medicines known as immunosuppressive agents. It is used together with other medicines to prevent the body from rejecting a transplanted kidney.

When a patient receives a kidney transplant, the body's white blood cells will try to get rid of (reject) the transplanted kidney. Belatacept works by suppressing the immune system and prevents the white blood cells from trying to get rid of the transplanted organ.

belatacept is to be given only by or under the direct supervision of a doctor.

Proper Use of belatacept

A nurse or other trained health professional will give you belatacept in a hospital. belatacept is given through a needle placed in one of your veins. The medicine must be injected slowly, so the needle will need to stay in place for at least 30 minutes.

belatacept comes with a Medication Guide. It is very important that you read and understand this information. Be sure to ask your doctor about anything you do not understand.

belatacept Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

More common
  • Abdominal or stomach pain
  • agitation
  • black, tarry stools
  • bladder pain
  • bloating or swelling of the face, arms, hands, lower legs, or feet
  • bloody or cloudy urine
  • blurred vision
  • bone pain
  • burning while urinating
  • chest pain
  • chills
  • coma
  • confusion
  • convulsions
  • cough or hoarseness
  • decreased frequency or amount of urine
  • decreased urine output
  • depression
  • difficult or labored breathing
  • difficult, burning, or painful urination
  • dizziness
  • dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
  • drowsiness
  • dry mouth
  • fainting
  • fast or irregular heartbeat
  • fever
  • frequent urge to urinate
  • headache
  • hostility
  • inability to move the arms and legs
  • increased blood pressure
  • increased thirst
  • irritability
  • itching in other skin areas
  • lethargy
  • loss of appetite
  • loss of bladder control
  • lower back or side pain
  • mood or mental changes
  • muscle pain or cramps
  • muscle spasms (tetany) or twitching
  • nausea or vomiting
  • nervousness
  • numbness or tingling in the hands, feet, or lips
  • pale skin
  • pounding in the ears
  • rapid weight gain
  • scaling
  • shortness of breath
  • slow or fast heartbeat
  • sore throat
  • sores, ulcers, or white spots on the lips or in the mouth
  • stupor
  • sudden decrease in the amount of urine
  • sudden numbness and weakness in the arms and legs
  • sweating
  • swelling of the face, ankles, or hands
  • swollen glands
  • tightness in the chest
  • trembling
  • troubled breathing
  • troubled breathing with exertion
  • unusual bleeding or bruising
  • unusual tiredness or weakness
  • unusual weight gain or loss
  • weakness or heaviness of the legs
  • weight gain
  • wheezing
Less common
  • Back pain
  • coughing or spitting up blood
  • drowsiness
  • joint pain, stiffness, or swelling
  • loss of appetite
  • night sweats
  • persistent non-healing sore
  • pink growth reddish patch or irritated area
  • shiny bump
  • sudden high fever or low-grade fever for months
  • swelling of the feet or lower legs
  • weight gain
  • white, yellow, or waxy scar-like area

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common
  • Abdominal or stomach cramps
  • blemishes on the skin
  • body aches or pain
  • collection of blood under the skin
  • cough producing mucus
  • deep, dark purple bruise
  • diarrhea
  • difficulty having a bowel movement (stool)
  • difficulty with moving
  • dry mouth
  • ear congestion
  • flushed, dry skin
  • fruit-like breath odor
  • hair loss or thinning of the hair
  • increased hunger
  • increased sweating
  • increased urination
  • itching, pain, redness, or swelling
  • loss of consciousness
  • loss of voice
  • muscle cramps in the hands, arms, feet, legs, or face
  • muscle or bone pain
  • muscle pain or stiffness
  • numbness and tingling around the mouth, fingertips, or feet
  • pain in the joints
  • pimples
  • shakiness in the legs, arms, hands, or feet
  • shortness of breath
  • sleeplessness
  • sneezing
  • swelling or inflammation of the mouth
  • tightness in the chest
  • tremor
  • trouble sleeping
  • unable to sleep
  • unexplained weight loss

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Interactions

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

Some products that may interact with this drug include: other drugs that weaken the immune system/increase the risk of infection (such as natalizumab, rituximab).

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