Name: Belinostat Intravenous
- Belinostat Intravenous brand name
- Belinostat Intravenous dosage
- Belinostat Intravenous dosage forms
- Belinostat Intravenous injection
- Belinostat Intravenous used to treat
- Belinostat Intravenous is used to treat
- Belinostat Intravenous side effects
- Belinostat Intravenous how to use
- Belinostat Intravenous drug
- Belinostat Intravenous works by
Commonly used brand name(s)
In the U.S.
Available Dosage Forms:
- Powder for Solution
Pharmacologic Class: Histone Deacetylase Inhibitor
Uses For belinostat
Belinostat injection is used to treat peripheral T-cell lymphoma in patients who have been treated with other medicines that did not work well.
belinostat is to be given only by or under the direct supervision of your doctor.
Precautions While Using belinostat
Your doctor will check your progress closely while you are receiving belinostat. This will allow your doctor to see if the medicine is working properly and to decide if you should continue to receive it. Blood tests may be needed to check for unwanted effects.
Using belinostat while you are pregnant can harm your unborn baby. Use an effective form of birth control to keep from getting pregnant. If you think you have become pregnant while using belinostat, tell your doctor right away.
belinostat can temporarily lower the number of white blood cells and platelets in your blood, increasing the chance of getting an infection. Avoid being near people who are sick or have infections. Wash your hands often. Tell your doctor if you have ever had an infection that would not go away or an infection that kept coming back. Check with your doctor right away if you think you are getting an infection or if you have a fever or chills, cough or hoarseness, lower back or side pain, or painful or difficult urination.
Check with your doctor right away if you have pain or tenderness in the upper stomach, pale stools, dark urine, loss of appetite, nausea, vomiting, or yellow eyes or skin. These could be symptoms of a serious liver problem.
belinostat may cause a serious type of reaction called tumor lysis syndrome. Your doctor may give you a medicine to help prevent this. Call your doctor right away if you have a decrease or change in urine amount, joint pain, stiffness, or swelling, lower back, side, or stomach pain, a rapid weight gain, swelling of the feet or lower legs, or unusual tiredness or weakness.
Belinostat can cause diarrhea, nausea, or vomiting. Your doctor may give you medicines to help prevent this. Call your doctor if you continue to have diarrhea, nausea, or vomiting after your dose.
belinostat Side Effects
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor or nurse immediately if any of the following side effects occur:More common
- Black, tarry stools
- bleeding gums
- bloating or swelling of the face, arms, hands, lower legs, or feet
- blood in the urine or stools
- bluish color
- blurred vision
- changes in skin color
- chest pain
- decreased urine
- dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
- dry mouth
- fast heartbeat
- fever or chills
- increased thirst
- irregular heartbeat
- loss of appetite
- mood changes
- muscle pain or cramps
- nausea or vomiting
- numbness or tingling in the hands, feet, or lips
- pale skin
- pinpoint red spots on the skin
- rapid, shallow breathing
- sore throat
- tightness in the chest
- troubled breathing with exertion
- unusual bleeding or bruising
- unusual tiredness or weakness
- unusual weight gain or loss
- Abdominal or stomach pain or tenderness
- clay colored stools
- dark urine
- decreased appetite
- joint pain, stiffness, or swelling
- lower back or side pain
- skin rash or itching
- yellow eyes or skin
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:Incidence not known
- pain at the injection site
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
Belinostat is used to treat a certain type of cancer: peripheral T-cell lymphoma (PTCL). It is used when other drugs do not work or when the cancer comes back after treatment. Belinostat works by slowing or stopping the growth of cancer cells.
How to use Belinostat Solution, Reconstituted (Recon Soln)
Read the Patient Information Leaflet if available from your pharmacist before you start using belinostat and each time you get a refill. If you have any questions, ask your doctor or pharmacist.
This medication is given by a health care professional in a clinic or hospital. It is injected into a vein as directed by your doctor, usually once a day on days 1 through 5 of a 21-day treatment cycle. The injection is given slowly, usually over 30 minutes. Tell your doctor or nurse right away if you notice redness, pain, or swelling during your injection. If you have side effects during the injection, your infusion may be given over a longer time, changed, or temporarily stopped.
The dosage is based on your medical condition, body size, laboratory test results, and response to treatment.
To get the most benefit from this medication, do not miss any doses. To help you remember, mark the days when you are scheduled to receive treatment on your calendar.