Name: Lotronex oral
- Lotronex oral action
- Lotronex oral used to treat
- Lotronex oral is used to treat
- Lotronex oral side effects
- Lotronex oral drug
- Lotronex oral treats
What is alosetron?
Alosetron blocks the action of a chemical called serotonin in the intestines. This slows the movement of stools (bowel movements) through the intestines.
Alosetron is used to treat severe, chronic irritable bowel syndrome (IBS) in women who have had diarrhea as the main symptom for at least 6 months. Alosetron should be used only by women who have tried other IBS treatments without success. Alosetron has not been shown to be effective in men with IBS.
Alosetron is not a cure for irritable bowel syndrome. After you stop taking this medicine, your symptoms may return within 1 week.
Alosetron may also be used for purposes not listed in this medication guide.
Before taking this medicine
Do not take alosetron if you have ever had any of the following conditions:
constipation (especially if it is your main IBS symptom);
a history of severe or ongoing constipation;
obstruction or perforation of your intestines;
Crohn's disease, ulcerative colitis, or diverticulitis;
blood clots, or circulation problems affecting your intestines;
severe liver disease; or
a condition for which you also take fluvoxamine (Luvox).
Alosetron is not expected to harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.
It is not known whether alosetron passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.
Alosetron is not approved for use by anyone younger than 18 years old.
How should I take alosetron?
Do not start taking alosetron if you are constipated. Stop taking the medicine and call your doctor if you become constipated.
Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results. Do not use this medicine in larger or smaller amounts or for longer than recommended.
Read all patient information, medication guides, and instruction sheets provided to you. Ask your doctor or pharmacist if you have any questions.
You may take alosetron with or without food.
Alosetron does not improve the symptoms of IBS for everyone. This medicine can help reduce stomach pain and discomfort, bowel urgency, and diarrhea. Some or all symptoms may improve within 1 to 2 weeks of treatment.
Stop taking alosetron and call your doctor if your IBS symptoms do not improve after 4 weeks of treatment.
If you stop taking alosetron for any reason, do not start taking it again without your doctor's advice.
Store at room temperature away from moisture, heat, and light.
Alosetron side effects
Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Serious or fatal side effects on the stomach and intestines have occurred in some people taking alosetron. In rare cases, alosetron has caused severe constipation, or ischemic colitis (caused by reduced blood flow to the intestines).
Stop taking alosetron and call your doctor right away if you develop:
new or worsening constipation;
bright or dark red blood in your stools; or
You may need to permanently discontinue alosetron if you have these side effects.
Older adults and those who are ill or debilitated may be more likely to have serious complications from constipation.
Common side effects may include:
pain or discomfort in your stomach or intestines.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What other drugs will affect alosetron?
Many drugs can interact with alosetron, and some drugs should not be used together. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide. Tell your doctor about all medicines you use, and those you start or stop using during your treatment with alosetron. Give a list of all your medicines to any healthcare provider who treats you.