Roxadustat
Name: Roxadustat
Dosing & Uses
Anemia of Chronic Kidney Disease
Pending FDA approval for treatment of anemia of chronic kidney disease in both non-dialysis-dependent and dialysis-dependent patients
Pharmacology
Mechanism of Action
Hypoxia-inducible factor prolyl hydroxylase inhibitor (HIF-PHI); promotes coordinated erythropoiesis through increasing endogenous erythropoietin, improving iron availability, and reducing hepcidin